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69293

Sucralose

≥98.0% (HPLC)

Synonym(s):

1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose

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Pack SizeSKUAvailabilityPrice
100 g

Estimated to ship onMay 04, 2026fromMilliporeSigma Canada Ltd.

$214.00

About This Item

Empirical Formula (Hill Notation):
C12H19Cl3O8
CAS Number:
56038-13-2
Molecular Weight:
397.63
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
329761543
EC Number:
259-952-2
Beilstein/REAXYS Number:
3654410
MDL number:
MFCD03648615

$214.00

Estimated to ship onMay 04, 2026Details

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Quality Level

200

assay

≥98.0% (HPLC)

form

powder

optical activity

[α]/D 86.0±2.0°, c = 1 in H2O

sweetness

600 × sucrose

color

white to off-white

useful pH range

6-8 (20 °C, 100 g/L)

mp

114.5  °C ((238.1 °F ) - OECD Test Guideline 102)

solubility

~300 g/L at 25 °C (77 °F)

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

Application

LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide
Sucralose is a non-caloric sugar used as a sweetener that activates T1R2/T1R3 sweet taste receptors and modulates glucagon-like peptide-1, glucose-dependent insulinotrophic peptide, and incretin secretion.

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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Show Differences

1 of 1

This Item
Y0001344PHR134284100
Sucralose ≥98.0% (HPLC)

Sigma-Aldrich

69293

Sucralose

Sucralose European Pharmacopoeia (EP) Reference Standard

Y0001344

Sucralose

Sucralose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1342

Sucralose

Sucrose ACS reagent, suitable for microbiology, ≥99.0%

Millipore

84100

Sucrose

assay

≥98.0% (HPLC)

assay

-

assay

-

assay

≥99.0% (HPLC)

solubility

~300 g/L at 25 °C (77 °F)

solubility

-

solubility

-

solubility

H2O: 0.1 g/mL, clear, colorless

Quality Level

200

Quality Level

-

Quality Level

300

Quality Level

200

form

powder

form

-

form

-

form

powder

color

white to off-white

color

-

color

-

color

-

mp

114.5  °C ((238.1 °F ) - OECD Test Guideline 102)

mp

-

mp

-

mp

185-187 °C (lit.)

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF8350V
BCCP6618
BCCN7504
0000487388
0000487388

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Nimesh Shukla et al.
Archives of biochemistry and biophysics, 639, 38-43 (2017-12-31)
Sucralose is a commonly employed artificial sweetener that appears to destabilize protein native structures. This is in direct contrast to the bio-preservative nature of its natural counterpart, sucrose, which enhances the stability of biomolecules against environmental stress. We have further
Virender K Sharma et al.
Chemosphere, 87(6), 644-648 (2012-02-22)
The kinetics of the oxidation of sucralose, an emerging contaminant, and related monosaccharides and disaccharides by ferrate(VI) (Fe(VI)) were studied as a function of pH (6.5-10.1) at 25°C. Reducing sugars (glucose, fructose, and maltose) reacted faster with Fe(VI) than did
Christopher B Forsyth et al.
PloS one, 6(12), e28032-e28032 (2011-12-07)
Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging. The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main component is alpha-synuclein protein. The finding of these Lewy bodies in the intestinal enteric nerves
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Global Trade Item Number

SKUGTIN
504746000104055977244090
I6138-50MG04061832091525
I6138-100MG04061832091518
69293-100G04061832768755

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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