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72301

9-(2-Carboxy-2-cyanovinyl)julolidine

BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

Synonym(s):

9-([E]-2-Carboxy-2-cyanovinyl)julolidine, CCVJ

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5 mg

Available to ship TODAYfromMILWAUKEE

$306.00

About This Item

Empirical Formula (Hill Notation):
C16H16N2O2
CAS Number:
Molecular Weight:
268.31
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:

$306.00


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product line

BioReagent

Quality Level

assay

≥97.0% (HPLC)

form

solid

solubility

DMSO: soluble, chloroform: soluble

fluorescence

λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol

suitability

suitable for fluorescence

SMILES string

OC(=O)\C(=C\c1cc2CCCN3CCCc(c1)c23)C#N

InChI

1S/C16H16N2O2/c17-10-14(16(19)20)9-11-7-12-3-1-5-18-6-2-4-13(8-11)15(12)18/h7-9H,1-6H2,(H,19,20)/b14-9+

InChI key

JXENNHTVELFRHV-NTEUORMPSA-N

Application

Fluorescent probe for binding to proteins etc., quantum yield increases by decreasing free rotation: fluorescent molecular rotor.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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723352188232670
suitability

suitable for fluorescence

suitability

suitable for fluorescence

suitability

suitable for fluorescence

suitability

suitable for fluorescence

fluorescence

λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol

fluorescence

λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol

fluorescence

λex 504 nm; λem 529 nm in 0.1 M Tris pH 8.0

fluorescence

λex 340 nm; λem 488 nm (nur DAPI), λex 364 nm; λem 454 nm (DAPI-DNA-Komplex), λex 374 nm; λem 461 nm in 10 mM Tris; 1 mM EDTA; pH 8.0; DNA

form

solid

form

crystals

form

solid

form

powder

solubility

DMSO: soluble, chloroform: soluble

solubility

DMSO: soluble, chloroform: soluble

solubility

DMF: soluble, DMSO: soluble, H2O: soluble (pH ≥ 5)

solubility

DMF: soluble, H2O: soluble

assay

≥97.0% (HPLC)

assay

≥97.0% (HPLC)

assay

≥95% (TLC)

assay

≥95.0% (HPLC)

product line

BioReagent

product line

BioReagent

product line

BioReagent

product line

BioReagent


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Christopher Rumble et al.
The journal of physical chemistry. A, 116(44), 10786-10792 (2012-10-27)
The photochemistry of the rotor probe 9-(2-carboxy-2-cyanovinyl)julolidine (CCVJ) was studied to elucidate a curious effect of fluid flow previously reported. The apparent sensitivity to fluid motion observed in CCVJ but not in the closely related molecule 9-(dicyanovinyl)julolidine (DCVJ) is found
Elisabeth Ablinger et al.
International journal of pharmaceutics, 441(1-2), 255-260 (2012-12-04)
A differential scanning fluorimetry (DSF) based high-throughput screening assay with the fluorescent molecular rotor CCVJ (9-(2-carboxy-2-cyanovinyl)julolidine) was developed. CCVJ is mainly sensitive to viscosity and less to polarity in comparison to polarity-sensitive dyes like SYPRO Orange, which was commonly used
James A Levitt et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 12(3), 662-672 (2011-02-18)
We present polarization-resolved fluorescence measurements of fluorescent molecular rotors 9-(2-carboxy-2-cyanovinyl)julolidine (CCVJ), 9-(2,2-dicyanovinyl)julolidine (DCVJ), and a meso-substituted boron dipyrromethene (BODIPY-C(12)). The photophysical properties of these molecules are highly dependent on the viscosity of the surrounding solvent. The relationship between their quantum



Global Trade Item Number

SKUGTIN
R-070-C04053252614279
R-070-B04053252665240
R-070-BK04053252890697
72301-5MG04061833278192

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