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P9172

Pyronin Y

for NA electrophoresis

Synonym(s):

Pyronin J, Pyronin Y, Pyronin G

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1 g
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$75.00
5 g
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$279.00

About This Item

Empirical Formula (Hill Notation):
C17H19ClN2O
CAS Number:
92-32-0
Molecular Weight:
302.80
EC Number:
202-147-8
UNSPSC Code:
12171500
NACRES:
NA.52
PubChem Substance ID:
57654569
MDL number:
MFCD00011725
Beilstein/REAXYS Number:
3795789
Colour Index Number:
45005

$75.00

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grade

Molecular Biology

Quality Level

200

form

powder

composition

Dye content, ≥45%

technique(s)

nucleic acid detection: suitable

mp

250-260 °C (lit.)

solubility

water: 10 mg/mL, dark red

suitability

suitable for nucleic acid staining

storage temp.

room temp

SMILES string

[Cl-].CN(C)c1ccc2C=C3C=C\C(C=C3Oc2c1)=[N+](/C)C

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This Item
21351983200P6892
Pyronin Y for NA electrophoresis

Sigma-Aldrich

P9172

Pyronin Y

Pyronin Y certified by the BSC, Dye content 50 %

Sigma-Aldrich

213519

Pyronin Y

Pyronin Y suitable for microscopy

Sigma-Aldrich

83200

Pyronin Y

Pyronin B Dye content ≥30 %

Sigma-Aldrich

P6892

Pyronin B

grade

Molecular Biology

grade

-

grade

-

grade

-

technique(s)

nucleic acid detection: suitable

technique(s)

-

technique(s)

-

technique(s)

-

suitability

suitable for nucleic acid staining

suitability

-

suitability

suitable for microscopy

suitability

-

form

powder

form

powder or crystals

form

-

form

powder

composition

Dye content, ≥45%

composition

Dye content, 50%

composition

-

composition

Dye content, ≥30%

solubility

water: 10 mg/mL, dark red

solubility

-

solubility

water: 0.01 g/10 mL, red

solubility

water: 1 mg/mL

Application

Pyronin Y has been used:
  • in the purification of quiescent and cycling hematopoietic stem cells and staining of bone marrow cells (HSCs)
  • as a component of the polychlorinated biphenyls (PCBS) solution for staining mammary gland side population cells (MG-SPs)
  • staining of CD34+ cells

Biochem/physiol Actions

Pyronin Y is a cationic dye that intercalates RNA and is visible as a red band during electrophoresis. It has also been shown to accumulate in mitochondria of viable cells. In conjuction with Methyl Green or Nancy-520, Pyronin Y can be used as a fluorescent differential stain of nucleic acids in paraffin tissue sections.

Preparation Note

This product is soluble in water 1 mg/ml, yielding a clear dark red solution.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000256525
0000256525
SHBP6260
SHBP3367
SHBN0822

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Gene expression differences between enriched normal and chronic myelogenous leukemia quiescent stem/progenitor cells and correlations with biological abnormalities
Affer M, et al.
Journal of Oncology, 2011 (2011)
Transcriptional profiling of mammary gland side population cells
Behbod F, et al.
Stem Cells, 24(4), 1065-1074 (2006)
A gel electrophoresis method for determining the relative binding constants of biologically active, intercalating fluorescent stains.
S M Hassur et al.
Analytical biochemistry, 95(2), 329-339 (1979-06-01)
Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres
Wang J, et al.
Blood, 124(22), 3237-3240 (2014)
Photosensitizing effects of the tricyclic heteroaromatic cationic dyes pyronin Y and toluidine blue O (tolonium chloride
Darzynkiewicz Z and Carter SP
Cancer research, 48(5) (1988)
View All Related Papers

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Global Trade Item Number

SKUGTIN
P9172-5G04061834402589
P9172-1G04061834402572

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