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A2580

Angiotensin Converting Enzyme from porcine kidney

lyophilized powder, ≥10 units/mg protein (Bradford)

Synonym(s):

ACE, Peptidyl-dipeptidase A

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Size/SKUAvailabilityPrice
0.1 unit
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$422.00
0.5 unit
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$1,200.00
1 unit
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$2,140.00

About This Item

CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.32
EC Number:
MDL number:
eCl@ss:
42010109
Specific activity:
≥10 units/mg protein (Bradford)

$422.00


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form

lyophilized powder

Quality Segment

specific activity

≥10 units/mg protein (Bradford)

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

pig ... ACE(613133)

General description

Angiotensin converting enzyme (ACE) is encoded by the gene, mRNA-decapping enzyme subunit 1 (DCP1). It is a zinc metalloprotease, which belongs to the M2 family.
ACE is a monomer with molecular weight of ~170 kDa
pH range for activity: 7-8.5
Temperature optimum: 37 °C
Zinc is required for activity
Inhibitors: captopril, enalaprilat, lisinopril etc. (1-10 μM)

Application

Angiotensin converting enzyme from porcine kidney has been used in in vitro angiotensin-converting enzyme (ACE) inhibition assay.

Biochem/physiol Actions

Angiotensin converting enzyme (ACE) catalyzes the conversion of angiotensin I to angiotensin II, which regulates the fluid-electrolyte balance and systemic blood pressure. ACE inhibits the vasodilator, bradykinin. ACE inhibitors are used to treat high blood pressure.
Removes C-terminal dipeptides from susceptible substrates, e.g., angiotensin I and bradykinin.

Physical form

Lyophilized powder containing Tris buffer salts.

Other Notes

One unit will produce 1.0 ·μmole of hippuric acid from Hippuryl-His-Leu per min in 50 mM HEPES and 300 mM NaCl at pH 8.3 at 37 °C.

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SAE0075P6675L5006
description

lyophilized powder, ≥10 units/mg protein (Bradford)

description

recombinant, ≥10 U/mg, expressed in HEK 293 cells

description

lyophilized powder, ≥100 units/mg protein

description

Type IV-S, ammonium sulfate suspension, 10-40 units/mg protein (Bradford)

specific activity

≥10 units/mg protein (Bradford)

specific activity

≥10 U/mg

specific activity

≥100 units/mg protein

specific activity

10-40 units/mg protein (Bradford)

Gene Information

pig ... ACE(613133)

Gene Information

-

Gene Information

-

Gene Information

-

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

ammonium sulfate suspension

shipped in

dry ice

shipped in

dry ice

shipped in

-

shipped in

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

UniProt accession no.

A0A480IQM9

UniProt accession no.

P12821

UniProt accession no.

-

UniProt accession no.

-


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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