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B1395

Anti-Bovine IgG (whole molecule) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

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2 mL
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$266.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162167
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), QPA
Citations:
7

$266.00

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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

indirect ELISA: 1:150,000, quantitative precipitin assay: 2.0 mg/mL

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Immunoglobulins (Igs) belong to the immunoglobulin super-family. Each immunoglobin has two heavy (H) and two light (L) chains, held together by disulphide linkages. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. Each light chain comprises of one variable N-terminal region and a constant C-terminal region. The four classes of IgG include IgG1, IgG2, IgG3 and IgG4, among them IgG1 is most abundant.

Application

Anti-Bovine IgG (whole molecule) antibody produced in rabbit may be used for indirect ELISA at a working dilution of 1:150,000. It was used in fluorescence immunoassay for quantitative determination of IgG in bovine milk.

Biochem/physiol Actions

Deficiency of IgG1 results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections. IgG3 mediates effector functions. IgG4 is associated with asymptomatic infection. IgG antibody have enormous therapeutic potential and the Fc region is involved in the development of therapeutic antibody.
Digestion of IgG by papain results in generation of fragment antigen binding (Fab). Pepsin digestion of IgG results in fragment crystallisable (fc), comprises the H chain constant region. Deficiency of IgG1 results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections. IgG3 mediates effector functions. IgG4 is associated with asymptomatic infection. IgG antibody have enormous therapeutic potential and the Fc region is involved in the development of therapeutic antibody.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Anti-Bovine IgG (whole molecule) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution

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Anti-Bovine IgG (whole molecule) antibody produced in rabbit

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Sigma-Aldrich

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Anti-Bovine IgG (whole molecule) antibody produced in goat

Anti-Goat IgG (whole molecule) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

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Anti-Goat IgG (whole molecule) antibody produced in rabbit

Anti-Bovine IgG (whole molecule) antibody produced in rabbit whole antiserum

Sigma-Aldrich

B8395

Anti-Bovine IgG (whole molecule) antibody produced in rabbit

description

IgG fraction of antiserum, buffered aqueous solution

description

whole antiserum

description

affinity isolated antibody, buffered aqueous solution

description

whole antiserum

antibody form

IgG fraction of antiserum

antibody form

whole antiserum

antibody form

affinity isolated antibody

antibody form

whole antiserum

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

indirect ELISA: 1:150,000, quantitative precipitin assay: 2.0 mg/mL

technique(s)

quantitative precipitin assay: 2.8 mg/mL

technique(s)

indirect ELISA: 1:60,000, quantitative precipitin assay: 2.0 mg/mL

technique(s)

quantitative precipitin assay: 4.0 mg/mL, indirect ELISA: 1:150,000

biological source

rabbit

biological source

goat

biological source

rabbit

biological source

rabbit

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

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Storage Class

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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