Key Documents

Anti-Human IgG2−Biotin antibody, Mouse monoclonal

Name: Anti-Human IgG2−Biotin antibody, Mouse monoclonal
Brand: SIGMA
Price: 397.8 USD
Availability: InStock

clone HP-6014, purified from hybridoma cell culture

Synonym(s):

Monoclonal Anti-Human IgG2

Select a Size

Change View

Pack Size	SKU	Availability	Price
0.2 mL		Available to ship TODAYfromMILWAUKEE	$468.00 $397.80
0.5 mL		Check Cart for Availability	$935.00

About This Item

NACRES:

NA.46

UNSPSC Code:

12352203

Conjugate:

biotin conjugate

Clone:

HP-6014, monoclonal

Application:

ELISA (d)

Citations:

$397.80

List Price$468.00Save 15%

Web-Only Promotion

Available to ship TODAYDetails

Request a Bulk Order

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

mouse

Quality Level

200

conjugate

biotin conjugate

antibody form

purified from hybridoma cell culture

antibody product type

secondary antibodies

clone

HP-6014, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

direct ELISA: 1:30,000

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Description

General description

Monoclonal Anti-Human IgG2 (mouse IgG1 isotype) is derived from the hybridoma (HP-60141 ) produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgG is the most abundant serum immunoglobulins of the immune system. IgG2 is a subtype of IgG. IgG is secreted by B cells and is found in blood and extracellular fluids.

Application

Monoclonal Anti-Human IgG2−Biotin antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and immunoblot.

Biochem/physiol Actions

IgG provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Low IgG2 levels were found in patients with systemic lupus erythematosus (SLE) and juvenile diabetes melitus.

The antibody is specific for human IgG2 and is non-reactive with other IgG subclasses. This clone has been singled out as the most widely applicable IgG2 specific monoclonal antibody by the IUIS/WHO study.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	F9890	SAB4200769	F4891
Sigma-Aldrich B3398 Anti-Human IgG2−Biotin antibody, Mouse monoclonal	Sigma-Aldrich F9890 Anti-Human IgG4−FITC antibody, Mouse monoclonal	Sigma-Aldrich SAB4200769 Anti-Human IgG3-Peroxidase antibody, Mouse monoclonal	Sigma-Aldrich F4891 Anti-Goat/Sheep IgG−FITC antibody, Mouse monoclonal
conjugate biotin conjugate	conjugate FITC conjugate	conjugate peroxidase conjugate	conjugate FITC conjugate
antibody form purified from hybridoma cell culture	antibody form purified from hybridoma cell culture	antibody form purified from hybridoma cell culture	antibody form purified from hybridoma cell culture
biological source mouse	biological source mouse	biological source mouse	biological source mouse
technique(s) direct ELISA: 1:30,000	technique(s) dot immunobinding: 1:64 using using a 4-8 μg dot of human IgG4	technique(s) direct ELISA: 1:80,000-1:160,000 using 2 μg/mL human IgG3 for coating.	technique(s) dot immunobinding: 1:32, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20, particle immunofluorescence: 1:32
species reactivity human	species reactivity -	species reactivity human	species reactivity sheep, goat, bovine
isotype IgG1	isotype IgG1	isotype IgG1	isotype IgG1

Still not finding the right product?

Try our Product Selector Tool to narrow your options

Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000504971

0000519188

0000179745

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Immunoglobulin subclass deficiency

Hanson L A, et al.

The Pediatric Infectious Disease Journal, 7, 7-21 (1988)

Assessment of Echinococcus granulosus somatic protoscolex antigens for serological follow-up of young patients surgically treated for cystic echinococcosis.

Nadia Ben Nouir et al.

Journal of clinical microbiology, 46(5), 1631-1640 (2008-03-28)

Echinococcus granulosus protoscolex soluble somatic antigens (PSSAs) were assessed for their prognostic value in the serological follow-up of young patients treated for cystic echinococcosis (CE), compared to conventional hydatid fluid (HF) antigen. Based on different clinical courses and outcome of

Clinical features, prognostic factors, and antibody effects in anti-mGluR1 encephalitis.

Marianna Spatola et al.

Neurology, 95(22), e3012-e3025 (2020-09-16)

To clinically characterize patients with anti-metabotropic glutamate receptor (mGluR) 1 encephalitis, to identify prognostic factors, and to study the immunoglobulin G (IgG) subclasses and effects of antibodies on neuronal mGluR1 clusters. Clinical information on new and previously reported patients was

View All Related Papers

Global Trade Item Number

SKU	GTIN
B3398-.2ML	04061833427811
B3398-.5ML	04061833427866

Questions

Reviews

No rating value