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C130

Chloro-APB hydrobromide

solid

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Synonym(s):

(±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, (±)-SKF-82958 hydrobromide, 6-Chloro-N-allyl-SKF-38393 hydrobromide

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Size/SKUAvailabilityPrice
5 mg
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$196.00
25 mg

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$674.00

About This Item

Empirical Formula (Hill Notation):
C19H20ClNO2 · HBr
CAS Number:
Molecular Weight:
410.73
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Form:
solid

$196.00

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form

solid

Quality Segment

color

tan

solubility

H2O: 3.7 mg/mL, aqueous base: unstable, ethanol: soluble

storage temp.

2-8°C

SMILES string

Br.Oc1cc2C(CN(CCc2c(Cl)c1O)CC=C)c3ccccc3

InChI

1S/C19H20ClNO2.BrH/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13;/h2-7,11,16,22-23H,1,8-10,12H2;1H

InChI key

WLXGFAVTAAQOFH-UHFFFAOYSA-N

Gene Information

human ... DRD1(1812)

Application

Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.

Biochem/physiol Actions

Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.

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This Item
D054SML0513S178
description

solid

description

≥98% (HPLC), solid

description

-

description

solid

form

solid

form

solid

form

-

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

-

solubility

H2O: 3.7 mg/mL, ethanol: soluble, aqueous base: unstable

solubility

H2O: >5 mg/mL

solubility

-

solubility

H2O: 7.5 mg/mL, DMSO: soluble

color

tan

color

white

color

-

color

white

Gene Information

human ... DRD1(1812)

Gene Information

human ... DRD1(1812)

Gene Information

-

Gene Information

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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