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C2522

Carbonic Anhydrase Isozyme II from bovine erythrocytes

lyophilized powder, ≥3,000 W-A units/mg protein

Synonym(s):

Carbonate Dehydratase, Carbonate Hydrolyase, Carbonic Anhydrase II

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Size/SKUAvailabilityPrice
5 mg

Estimated to ship onOctober 30, 2026fromMILWAUKEE

$192.00
25 mg

Estimated to ship onOctober 30, 2026fromMILWAUKEE

$658.00
100 mg

Estimated to ship onOctober 30, 2026fromMILWAUKEE

$2,190.00

About This Item

CAS Number:
9001-03-0
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-576-6
MDL number:
MFCD00081467
EC Number:
4.2.1.1 (BRENDA, IUBMB)
Specific activity:
≥2475 units/mg solid, ≥3,000 W-A units/mg protein
Biological source:
bovine erythrocytes

$192.00

Estimated to ship onOctober 30, 2026Details

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biological source

bovine erythrocytes

Quality Segment

form

lyophilized powder

specific activity

≥2475 units/mg solid, ≥3,000 W-A units/mg protein

mol wt

30 kDa

pI 

~5.9

storage temp.

−20°C

Application

Carbonic anhydrase from sigma has been used for the analysis of thermodynamic stability of the enzyme by measuring the binding affinity and stoichiometry. The enzyme has also been used to generate CD4+ T cell lines specific for carbonic anhydrase during the study of autoimmune pancreatitis in rat.

Biochem/physiol Actions

Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30,000 Da. The enzyme catalyzes the hydration of carbon dioxide to carbonic acid. It is involved in many physiological and pathological processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, inhibitors that block this enzyme can have therapeutic implications in glaucoma, epilepsy and Parkinson′s disease.

Other Notes

One Wilbur-Anderson (W-A) unit will cause the pH of a 0.02 M Trizma buffer to drop from 8.3 to 6.3 per min at 0 °C. (One W-A unit is essentially equivalent to one Roughton-Booth unit.)

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Carbonic Anhydrase Isozyme II from bovine erythrocytes lyophilized powder, ≥3,000 W-A units/mg protein

Sigma-Aldrich

C2522

Carbonic Anhydrase Isozyme II from bovine erythrocytes

Carbonic Anhydrase Isozyme II from bovine erythrocytes lyophilized powder, ≥2,000 W-A units/mg protein

Sigma-Aldrich

C3640

Carbonic Anhydrase Isozyme II from bovine erythrocytes

Carbonic Anhydrase Isozyme II from bovine erythrocytes Isoelectric focusing marker, pI 5.4

Sigma-Aldrich

C3666

Carbonic Anhydrase Isozyme II from bovine erythrocytes

Carbonic Anhydrase Isozyme II human ≥80%, powder, ≥3,000 W-A units/mg protein

Sigma-Aldrich

C6165

Carbonic Anhydrase Isozyme II human

description

lyophilized powder, ≥3,000 W-A units/mg protein

description

lyophilized powder, ≥2,000 W-A units/mg protein

description

Isoelectric focusing marker, pI 5.4

description

≥80%, powder, ≥3,000 W-A units/mg protein

biological source

bovine erythrocytes

biological source

-

biological source

-

biological source

-

specific activity

≥2475 units/mg solid, ≥3,000 W-A units/mg protein

specific activity

≥2,000 W-A units/mg protein

specific activity

-

specific activity

≥3,000 W-A units/mg protein

form

lyophilized powder

form

lyophilized powder

form

powder

form

powder

mol wt

30 kDa

mol wt

-

mol wt

-

mol wt

30 kDa

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

300

Quality Level

200

Quality Level

200

Quality Level

200

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Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Codes

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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