C4382 (98%) and C2409 (99%) are the same chemical with slightly different purity specifications. Product No. C2409 is no longer available.
C4382
Carbamoylcholine chloride
≥98% (titration), Non-selective cholinergic agonist, crystalline
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Synonym(s):
(2-Hydroxyethyl)trimethylammonium chloride carbamate, Carbachol, Carbamylcholine chloride
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| Size/SKU | Availability | Price |
|---|---|---|
1 g | Check Cart for Availability | $129.00 |
10 g | Check Cart for Availability | $558.00 |
25 g | Estimated to ship onOctober 16, 2026fromMILWAUKEE | $1,000.00 |
About This Item
Linear Formula:
NH2COOCH2CH2N(Cl)(CH3)3
CAS Number:
Molecular Weight:
182.65
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-127-3
MDL number:
Beilstein/REAXYS Number:
3917459
Assay:
≥98% (titration)
Form:
crystalline
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Product Name
Carbamoylcholine chloride, ≥98% (titration), crystalline
Quality Segment
assay
≥98% (titration)
form
crystalline
color
white
mp
210 °C (dec.) (lit.)
solubility
H2O: 1 g/mL, ethanol: 20 mg/mL
SMILES string
[Cl-].C[N+](C)(C)CCOC(N)=O
InChI
1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
InChI key
AIXAANGOTKPUOY-UHFFFAOYSA-N
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133), CHRNA2(1135)
mouse ... Chrm1(12669)
rat ... Chrm1(25229), Chrm2(81645), Chrm3(24260), Chrna2(170945), Chrna3(25101), Chrna4(25590)
Application
Carbamoylcholine chloride has been used:
- to stimulate insulin secretion in transgenic mice
- to induce contraction of undifferentiated and differentiated human adipose-derived stem cells (hASCs)
- to mediate constriction of iris in pupillary light reflex studies in mice
Biochem/physiol Actions
Non-selective cholinergic agonist that is resistant to the action of cholinesterases; inhibits apoptotic death of cultured neurons, and may induce apoptosis in thymocytes.
Carbachol elicits tear fluid secretion by interacting with muscarinic receptors. It is an analog of acetylcholine and an antiglaucoma drug. In ciliary processes, carbachol along with nitric oxide (NO) regulates Na+ and K+-ATPase activity. It stimulates insulin vesicles transport to the secretory site to increase insulin secretion.
Features and Benefits
This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| description ≥98% (titration), crystalline | description United States Pharmacopeia (USP) Reference Standard | description Pharmaceutical Secondary Standard; Certified Reference Material | description European Pharmacopoeia (EP) Reference Standard |
| form crystalline | form - | form - | form - |
| assay ≥98% (titration) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level - | Quality Level 300 | Quality Level - |
| solubility ethanol: 20 mg/mL, H2O: 1 g/mL | solubility - | solubility - | solubility - |
| color white | color - | color - | color - |
| Gene Information human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133), CHRNA2(1135) | Gene Information human ... CHRM3(1131) | Gene Information human ... CHRM3(1131) | Gene Information human ... CHRM3(1131) |
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Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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What is the difference between Carbamoylcholine chloride Products C4382 and C2409?
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How should Carbamoylcholine chloride, Product C4382, be dissolved?
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This product is soluble in water (1000 mg/mL), in ethanol (20 mg/mL), and in methanol (100 mg/mL).
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