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D4268

NG,NG-Dimethylarginine dihydrochloride

≥98% (TLC), powder, NOS inhibitor

Synonym(s):

asym-Dimethylarginine, ADMA

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Pack SizeSKUAvailabilityPrice
10 mg
Please contact Customer Service for Availability
$117.00
50 mg
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$420.00

About This Item

Empirical Formula (Hill Notation):
C8H18N4O2 · 2HCl
CAS Number:
Molecular Weight:
275.18
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (TLC)
Form:
powder

$117.00


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Product Name

NG,NG-Dimethylarginine dihydrochloride,

assay

≥98% (TLC)

Quality Segment

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

Cl[H].Cl[H].CN(C)C(=N)NCCC[C@H](N)C(O)=O

InChI

1S/C8H18N4O2.2ClH/c1-12(2)8(10)11-5-3-4-6(9)7(13)14;;/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14);2*1H/t6-;;/m0../s1

InChI key

SYLNVYJOPZWPJI-ILKKLZGPSA-N

General description

NG,NG-Dimethylarginine dihydrochloride is a methylated arginine derivative, which is produced by the liver. It is linked to liver cirrhosis, alcoholic hepatitis and acute liver failure (ALF).

Application

NG,NG- Dimethylarginine dihydrochloride has been used:
  • to study its effects on cardiovascular activities in rostral ventrolateral medulla (RVLM) in rats[1]
  • as a standard for measuring L-arginine and dimethylarginines
  • to study its effects on hepatic deterioration

Biochem/physiol Actions

Reversible inhibitor of nitric oxide synthetase in vivo and in vitro.

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This Item
M7033D0390724041
assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥99% (TLC)

assay

95% (CP)

form

powder

form

powder

form

powder

form

powder

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

−20°C

solubility

water: 50 mg/mL, clear, colorless

solubility

water: 49.00-51.00 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

methanol: 10 mg/mL

solubility

-

Gene Information

human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

Gene Information

human ... NOS1(4842), NOS2(4843), NOS3(4846)
mouse ... Nos2(18126)
rat ... Nos1(24598), Nos2(24599)

Gene Information

-

Gene Information

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research






Global Trade Item Number

SKUGTIN
D4268-10MG04061833564226
D4268-50MG04061833564233

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