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F4537

Fibroblast Growth Factor-5 human

Name: Fibroblast Growth Factor-5 human
Brand: SIGMA
Price: 669 CAD

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE and N-terminal analysis)

Synonyme(s) :

hFGF-5, FGF-5

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À vous/Référence	Disponibilité	Prix
50 μg	Veuillez contacter notre Service Clients pour connaître la disponibilité de ce produit.	669,00 $

A propos de cet article

UNSPSC Code:

12352202

NACRES:

NA.32

MDL number:

MFCD00212946

669,00 $

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Propriétés

biological source

human

Quality Segment

100

recombinant

expressed in E. coli

assay

≥97% (SDS-PAGE and N-terminal analysis)

form

lyophilized powder

potency

0.1-15.0 ng/mL

mol wt

27 kDa

packaging

pkg of 50 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P12034

storage temp.

−20°C

Gene Information

human ... FGF5(2250)

Description

Application

Fibroblast growth factor-5 human has been used for the induction of differentiation in E14Tg2a and 46C parental mouse ES (embryonic stem) cell lines, Fgf4^+/- (clone 342) ,Fgf4^-/- (clone FD6) ES cells and Erk2^+/- ES cells and Erk2^-/- ES cell lines.[1]

Biochem/physiol Actions

FGF5 (fibroblast growth factor 5) regulates hair growth cycle, and its inactivation in mice leads to angora phenotype. In the peripheral nervous system, it acts as a muscle-derived trophic factor for motor neurons. In vivo it demonstrates neurotrophic activity, and in vitro it influences astroglial characteristics. It functions as an oncogene in glioblastoma due to its autocrine and paracrine functions. Its expression is elevated in human astrocytic brain tumours, which is linked to increased malignancy.[2] It causes the regression of hair follicles, and thus, controls the length of hair in humans. It might have potential as a therapeutic target to control the growth of eyelashes.[3]

Physical form

Lyophilized from a 0.2 μm filtered solution in 10mM MOPS, 50 mM NaSO₄, 0.5 mM EDTA, 0.5 mM DTT and 5% trehalose, pH 7.0 containing 50 μg BSA per 1 μg cytokine.

Analysis Note

The biological activity is tested in culture with quiescent NR6R-3T3 fibroblasts.[4]

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Cet article	F5542	F7301	F8424
Sigma-Aldrich F4537 Fibroblast Growth Factor-5 human	Sigma-Aldrich F5542 Fibroblast Growth Factor-Acidic human	Sigma-Aldrich F7301 Fibroblast Growth Factor-18 human	Sigma-Aldrich F8424 Fibroblast Growth Factor-4 human
description recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE and N-terminal analysis)	description FGF-Acidic, recombinant, expressed in E. coli, suitable for cell culture	description >95% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder	description FGF-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli
biological source human	biological source human	biological source human	biological source human
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable
assay ≥97% (SDS-PAGE and N-terminal analysis)	assay ≥97% (SDS-PAGE)	assay >95% (SDS-PAGE and HPLC)	assay ≥95% (SDS-PAGE)
Quality Level 100	Quality Level 200	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder

Classe de stockage

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number

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Principaux documents

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Fibroblast Growth Factor-5 human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE and N-terminal analysis)

Sélectionner une taille de conditionnement

A propos de cet article

669,00 $

biological source

Quality Segment

recombinant

assay

form

potency

mol wt

packaging

storage condition

technique(s)

impurities

UniProt accession no.

storage temp.

Gene Information

Application

Biochem/physiol Actions

Physical form

Analysis Note

Comparer avec des articles similaires

Cet article

Informations sur la sécurité

Classe de stockage

wgk

flash_point_f

flash_point_c

ppe

Documentation

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Principaux documents

Passer à

Fibroblast Growth Factor-5 human

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥97% (SDS-PAGE and N-terminal analysis)

Sélectionner une taille de conditionnement

A propos de cet article

F4537-50UG

669,00 $

biological source

Quality Segment

recombinant

assay

form

potency

mol wt

packaging

storage condition

technique(s)

impurities

UniProt accession no.

storage temp.

Gene Information

Application

Biochem/physiol Actions

Physical form

Analysis Note

Comparer avec des articles similaires

Cet article

Informations sur la sécurité

Classe de stockage

wgk

flash_point_f

flash_point_c

ppe

Documentation

Certificats d'analyse (COA)

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