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I1020

IL-4 mouse

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

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Synonym(s):

Interleukin-4, mIL-4, Interleukin-4 human

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Size/SKUAvailabilityPrice
5 μg

Available to ship TODAYfromMILWAUKEE

$187.00

About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
MFCD00166698
Biological source:
mouse
Recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
~13.5 kDa
Impurities:
<0.1 EU/μg

$187.00

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Product Name

Interleukin-4 from mouse, IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

mouse

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized powder

potency

0.1-2.0 ng/mL ED50/EC50

quality

endotoxin tested

mol wt

~13.5 kDa

packaging

pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg

UniProt accession no.

P07750

storage temp.

−20°C

General description

Recombinant Interleukin‑4 from mouse (IL‑4; mIL‑4) is expressed in Escherichia coli and supplied as a lyophilized powder. IL‑4 is a lymphokine involved in the growth and differentiation of immune cells and is commonly used in mammalian cell culture research in vitro.

Application

Recombinant mouse IL‑4 has been used as a supplement in mammalian cell culture media, including class switch recombination assays and immune‑related in vitro research studies.

Biochem/physiol Actions

Interleukin‑4 (IL‑4) is an immunomodulatory cytokine that supports growth and differentiation of mmunologically competent cells. Recombinant mouse IL‑4 has been widely studied in cell‑based research models involving lymphocyte signaling, differentiation, and cytokine‑mediated cellular responses and VEGF‑induced and bFGF‑induced angiogenesis.
Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.
Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific.

Physical form

Lyophilized, 0.2 μm filtered, with no additives.

Analysis Note

The proliferative activity is tested in culture using mouse HT-2 cells.

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IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

mouse

biological source

mouse

biological source

mouse

biological source

human

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥98% (SDS-PAGE)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

mol wt

~13.5 kDa

mol wt

~21.7 kDa

mol wt

18 kDa

mol wt

14.9 kDa (containing 129 amino acid residues)

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCZ0627
    033K1298
    MKCK9251
    MKCJ6929
    MKCS7106

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