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IL-3 mouse

Name: IL-3 mouse
Brand: SIGMA
Price: 241 USD
Availability: InStock

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Synonym(s):

IL-3, mIL-3, Interleukin-3 from mouse

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Size/SKU	Availability	Price
10 μg	Available to ship TODAYfromMILWAUKEE	$241.00
50 μg	Available to ship TODAYfromMILWAUKEE	$603.00

About This Item

UNSPSC Code:

12352202

NACRES:

NA.77

MDL number:

MFCD00164817

Biological source:

mouse

Recombinant:

expressed in E. coli

Assay:

≥98% (SDS-PAGE)

Form:

lyophilized powder

Mol wt:

15.1 kDa

Impurities:

≤1.000 EU/μg

$241.00

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Properties

Product Name

Interleukin-3 from mouse, IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

biological source

mouse

Quality Segment

200

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized powder

potency

0.01-0.1 ng/mL ED₅₀/EC₅₀

quality

endotoxin tested

mol wt

15.1 kDa

packaging

pkg of 10 and 50 μg

technique(s)

cell culture | mammalian: suitable

impurities

≤1.000 EU/μg

color

white to yellow

UniProt accession no.

P01586

storage temp.

−20°C

Description

General description

Recombinant mouse Interleukin‑3 (IL‑3) is a hematopoietic cytokine expressed in E. coli and supplied as a lyophilized powder. IL‑3 is widely used in mammalian cell culture research involving hematopoietic and immune‑related cellular response studies in vitro.

Application

Recombinant mouse IL‑3 has been used as a supplement in mammalian cell culture media, including RPMI‑based systems, and in in vitro studies of immune and hematopoietic signaling pathways.

Biochem/physiol Actions

Interleukin‑3 (IL‑3) is a multifunctional cytokine that supports proliferation and differentiation of hematopoietic progenitor cells and has been extensively studied in in vitro cell‑based research models.

Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.

Physical form

Lyophilized with 0.5 mg of bovine serum albumin. Sterile filtered through a 0.2 μm filter.

Analysis Note

The biological activity is measured by the dose-dependent stimulation of the proliferation of mouse M-NFS-60 cells.

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This Item	I5286	I1646	I9646
Sigma-Aldrich I4144 Interleukin-3 from mouse	Sigma-Aldrich I5286 IL-3 from mouse	Sigma-Aldrich I1646 Interleukin-3 human	Sigma-Aldrich I9646 Interleukin-6 from mouse
description IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture	description Carrier free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), suitable for cell culture	description IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture	description IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, carrier free
recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli	recombinant expressed in E. coli
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
assay ≥98% (SDS-PAGE)	assay ≥98% (SDS-PAGE)	assay ≥97% (HPLC and SDS-PAGE)	assay ≥97% (SDS-PAGE)
biological source mouse	biological source mouse	biological source human	biological source mouse
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form lyophilized powder	form lyophilized	form lyophilized powder	form lyophilized powder

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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