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I6137

Monoclonal Anti-Bovine IgM antibody produced in mouse

clone BM-23, ascites fluid

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0.5 mL
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$623.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00164546
Technique(s):
indirect ELISA: 1:4,000, western blot: suitable, capture ELISA: suitable, immunoprecipitation (IP): suitable
Conjugate:
unconjugated
Application:
ELISA (c), ELISA (i), IP, WB
Citations:
8

$623.00

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biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

secondary antibodies

clone

BM-23, monoclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:4,000, western blot: suitable, capture ELISA: suitable, immunoprecipitation (IP): suitable

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Bovine IgMs are glycoprotein antibodies that regulate antigen binding during immunological responses. These antibodies have three isotypes, namely, IgMa, IgMb and IgMc. Structural restraints on movement enhance the complement-fixing functions of bovine IgMs . Monoclonal Anti-Bovine IgM antibody detects an epitope on the heavy chain of bovine IgM. The antibody reacts with bovine serum, but does not react with sera from human, baboon, marmoset, gibbon, rhesus, hamster, rabbit, goat, pig, dog, rat, turkey, chicken, or catfish. Furthermore, the product does not bind to native or reduced bovine light chains.
Monoclonal Anti-Bovine IgM (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgM is highly conserved antibody in vertebrates and is expressed early during immune response. It exists as pentamer and is secreted by peritoneal B cells.

Immunogen

Purified bovine IgM

Application

Monoclonal Anti-Bovine IgM antibody is suitable for use in indirect ELISA (1:1,000), western blot, immunoprecipitation and ELISA.

Biochem/physiol Actions

IgM plays a key role in engulfing of the of apoptotic cells. A reduction in serum IgM levels leads to increased autoimmune response and higher risk for infections. IgM displays polyreactive and autoreactive functionality. It plays a key role in tissue homeostasis by mediating clearance of tissue based molecules.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Monoclonal Anti-Bovine IgM antibody produced in mouse clone BM-23, ascites fluid

Sigma-Aldrich

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Monoclonal Anti-Bovine IgM antibody produced in mouse

Anti- Bovine IgG-Peroxidase antibody, Mouse monoclonal clone BG-18, purified from hybridoma cell culture

Sigma-Aldrich

SAB4200796

Anti- Bovine IgG-Peroxidase antibody, Mouse monoclonal

Monoclonal Anti-Bovine IgG antibody produced in mouse clone BG-18, ascites fluid

Sigma-Aldrich

B6901

Monoclonal Anti-Bovine IgG antibody produced in mouse

Monoclonal Anti-Goat/Sheep IgG antibody produced in mouse clone GT-34, ascites fluid

Sigma-Aldrich

G2904

Monoclonal Anti-Goat/Sheep IgG antibody produced in mouse

antibody form

ascites fluid

antibody form

purified from hybridoma cell culture

antibody form

ascites fluid

antibody form

ascites fluid

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

technique(s)

capture ELISA: suitable, indirect ELISA: 1:4,000, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

direct ELISA: 1:20,000-1:40,000 using 1 μg/ml bovine IgG for coating

technique(s)

dot blot: suitable, indirect ELISA: 1:1000

technique(s)

indirect ELISA: 1:10,000-1:20,000

conjugate

unconjugated

conjugate

peroxidase conjugate

conjugate

unconjugated

conjugate

unconjugated

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

clone

BM-23, monoclonal

clone

BG-18, monoclonal

clone

BG-18, monoclonal

clone

GT-34, monoclonal

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

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