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I9513

Monoclonal Anti-Human IgG2 (Fc specific) antibody produced in mouse

clone HP-6002, ascites fluid

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0.2 mL

Available to ship TODAYfromMILWAUKEE

$236.00
$200.60
0.5 mL

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$491.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162494
Conjugate:
unconjugated
Clone:
HP-6002, monoclonal
Application:
ELISA (i)
Citations:
17

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biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

secondary antibodies

clone

HP-6002, monoclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:2,000

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

IgG is the main antibody type found in plasma and extracellular fluid and is expressed on B cell membrane. IgG is further subdivided into four subclass- IgG1, IgG2, IgG3 and IgG4 and contribute 65, 30, 5 and 4% in total IgG. IgG2 produce in response to anti-polysaccharide. Monoclonal anti-human IgG2 (Fc specific) antibody can be used in indirect ELISA and Immunofluorometric Assay (IFMA). Mouse anti-human IgG2 (Fc specific) antibody reacts specifically with IgG2 of human but not with other IgG subclasses.

Immunogen

Purified human IgG myeloma proteins covalently linked to polyaminostyrene microbeads.

Application

Monoclonal Anti-Human IgG2 (Fc specific) antibody is suitable for use in ELISA.
Monoclonal anti-human IgG2 (Fc specific) antibody can be used to detect IgG2 subclass by using different immunoassays like- hemagglutination (HA), hemagglutination inhibition(HAI), Imprint Immunofixation (IIF) and Particle Counting Immunoassay (PACIA). It can also be used in immunohistological assays.

Biochem/physiol Actions

IgG2 immunoglobulin is a 146 kDa IgG subtype, which mediates immune response to the polysaccharide antigens of the bacterial capsule. Deficiency of IgG2 poses an increased risk to certain bacterial infections. IgG2 has the least affinity among the IgG subtypes to Fcγ receptors (FcγR). IgG2 exists in three forms namely, IgG2-A, -B, and -A/B. They show variation in the arrangement of fragment antigen binding domain (Fab) and hinge region.
Monoclonal Anti-Human IgG2 is specific for the IgG2 subclass and nonreactive with IgG1, IgG3, and IgG4 in an ELISA.

Physical form

This product is provided as ascites fluid with 15 mm sodium azide as a preservative.

Preparation Note

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Monoclonal Anti-Human IgG2 (Fc specific) antibody produced in mouse clone HP-6002, ascites fluid

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Sigma-Aldrich

I6760

Monoclonal Anti-Human IgG (Fc specific) antibody produced in mouse

description

clone HP-6002, ascites fluid

description

clone GG-7, ascites fluid

description

clone SG-16, ascites fluid

description

clone HP-6017, ascites fluid

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

indirect ELISA: 1:2,000

technique(s)

indirect ELISA: 1:40,000

technique(s)

indirect ELISA: 1:5,000

technique(s)

indirect ELISA: 1:3,000

isotype

IgG1

isotype

IgG1

isotype

IgG1

isotype

IgG2a

clone

HP-6002, monoclonal

clone

GG-7, monoclonal

clone

SG-16, monoclonal

clone

HP-6017, monoclonal

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Storage Class

12 - Non Combustible Liquids

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