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P1742

Prealbumin from human plasma

lyophilized powder

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Synonym(s):

Thyroxine binding prealbumin, Transthyretin

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0.5 mg
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$300.00
1 mg

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About This Item

CAS Number:
87090-18-4
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
MFCD00132069
Biological source:
human plasma
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized powder
Technique(s):
immunoelectrophoresis: suitable, immunoprecipitation (IP): suitable
Impurities:
Infectious agents, tested

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biological source

human plasma

Quality Segment

assay

≥95% (SDS-PAGE)

form

lyophilized powder

technique(s)

immunoelectrophoresis: suitable, immunoprecipitation (IP): suitable

impurities

Infectious agents, tested

solubility

H2O: soluble 1 mg/mL

ε (extinction coefficient)

13.5 at 280 nm at 1%

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... TTR(7276)

General description

Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver. It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry.

Application

Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer.
Prealbumin from human plasma has been used as a positive control in immunoprecipitation as a reference standard in quantitative rocket immunoelectrophoresis for quantification of cerebrospinal fluid.

Biochem/physiol Actions

Human prealbumin has been observed in carcinoid tumors.
Prealbumin levels are indictors of malnutrition and may be modulated during inflammation. It is regarded as potential marker of protein energy malnutrition (PEM) during chronic kidney failure supported dialysis. Low levels of prealbumin poses high risk to heart failure (HF).

Packaging

Package size based on protein content

Physical form

Lyophilized powder containing sodium phosphate and NaCl

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000582678
    0000582357
    0000581951
    0000576403
    0000481312

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    Questions

    1–7 of 7 Questions  

    1. Does this TTR (P1742) have thyroid hormone bound to it?

      1 answer

      1. This product is transthyretin (prealbumin) from human plasma. Although TTR can bind thyroid hormones, thyroid hormone content and/or its bound status to TTR are not specified or tested for this product.

        Helpful?

    2. How long does prealbumin from human plasma (product P1742) remain stable after being dissolved in water, and at what temperature should this solution be stored?

      1 answer

      1. Stock solutions are stable for up to 2 weeks when stored refrigerated at 4°C and up to 6 months when stored in aliquots at -20°C. Avoid repeated freeze/thaw cycles.

        Helpful?

    3. What is the volume from which Product P1742, Prealbumin from human plasma, is lyophilized from?

      1 answer

      1. The starting volume is lot specific. Please contact Technical Service to obtain the exact volume of your lot of interest.

        Helpful?

    4. What is the molecular weight of Product P1742, Prealbumin from human plasma?

      1 answer

      1. The molecular weight has been reported to be 54,980 Daltons. Referece: The Plasma Proteins, 2nd edition (1975) p. 60.

        Helpful?

    5. What is the solubility of Product P1742, Prealbumin from human plasma?

      1 answer

      1. This product is soluble in water at 1mg/mL.

        Helpful?

    6. What is the Department of Transportation shipping information for this product?

      1 answer

      1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

        Helpful?

    7. What is the purity of Product P1742, Prealbumin from human plasma?

      1 answer

      1. Information about purity can be found on the lot specific certificate of analysis.

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