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Guanidine hydrochloride

Name: Guanidine hydrochloride
Brand: SIGMA

anhydrous, free-flowing, Redi-Dri^™, ≥99%

Synonym(s):

Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride

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About This Item

Linear Formula:

NH₂C(=NH)NH₂ · HCl

CAS Number:

50-01-1

Molecular Weight:

95.53

NACRES:

NA.28

UNSPSC Code:

12352107

PubChem Substance ID:

329824214

EC Number:

200-002-3

Beilstein/REAXYS Number:

3591990

MDL number:

MFCD00013026

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Properties

grade

anhydrous

Quality Segment

100

product line

Redi-Dri^™

assay

≥99%

quality

free-flowing

pH

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)

solubility

H₂O: 6 M

density

1.3 g/cm³ (lit.)

absorption

≤0.10 at 260 nm in H₂O at 6 M

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

Description

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

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1 of 1

This Item	G4505	50933
Sigma-Aldrich RDD001 Guanidine hydrochloride	Sigma-Aldrich G4505 Guanidine hydrochloride	Sigma-Aldrich 50933 Guanidine hydrochloride
description anhydrous, free-flowing, Redi-Dri^™, ≥99%	description ≥99% (titration), organic base and chaeotropic agent	description BioUltra, Molecular Biology, ≥99.5% (AT)
grade anhydrous	grade -	grade Molecular Biology
assay ≥99%	assay ≥99% (titration)	assay ≥99.5% (AT)
density 1.3 g/cm³ (lit.)	density 1.3 g/cm³ (lit.)	density 1.3 g/cm³ (lit.)
Quality Level 100	Quality Level 400	Quality Level 200
product line Redi-Dri^™	product line -	product line BioUltra
mp 180-185 °C (lit.)	mp 180-185 °C (lit.)	mp 180-185 °C (lit.)

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Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H302 + H332,H315,H319

Precautionary Statements

P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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