The stability of this product in solution has not been determined. The solubility of this material is tested at 50 mg/mL. Other sources report that this compound is also soluble at 100 mg/mL in DMSO. In addition, prepared solutions are stable for 1 month at -20°C and 6 months at -80°C. This information has not been validated.
S0375
D-Saccharic acid 1,4-lactone monohydrate
≥98.0% (HPLC)
Synonym(s):
D-Glucaric acid-1,4-lactone, D-Saccharolactone
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About This Item
Empirical Formula (Hill Notation):
C6H8O7 · H2O
CAS Number:
Molecular Weight:
210.14
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
85594
Pricing and availability is not currently available.
Quality Segment
assay
≥98.0% (HPLC)
form
powder
impurities
≤10.0% water (Karl Fischer)
color
white
mp
91 - 93 °C ((196 - 199 °F ))
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
SMILES string
O.O[C@@H]1[C@@H](O)C(=O)O[C@@H]1[C@H](O)C(O)=O
InChI
1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4+;/m1./s1
InChI key
NPFKVZHSFSFLPU-QGBSHYGGSA-N
General description
D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of β-glucuronidase enzyme.It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).
Application
D-Saccharic acid 1,4-lactone monohydrate has been used as a constituent of phosphate buffer to block incidental β-glucuronidase activity in Streptococcus pneumoniae hyaluronan lyase (SpnHL) activity assay. It has also been used as a component of reaction mixture in Iduronidase activity assay and UDP-glucuronosyltransferase 1 (UGT1A1) inhibition assay.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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This Item | |||
|---|---|---|---|
| description ≥98.0% (HPLC) | description ≥98% (GC) | description 98.5-102% (KT) | description analytical standard |
| assay ≥98.0% (HPLC) | assay ≥98% (GC) | assay 98.5-102% (KT) | assay - |
| solubility water: 50 mg/mL, clear, colorless to faintly yellow | solubility soluble, clear to very slightly hazy, colorless to faintly yellow | solubility - | solubility - |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form powder | form powder | form powder | form - |
| storage temp. 2-8°C | storage temp. room temp | storage temp. room temp | storage temp. 2-30°C |
| impurities ≤10.0% water (Karl Fischer) | impurities - | impurities - | impurities - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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