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S2812

SNC80

≥98% (HPLC), δ opioid receptor agonist, solid

Synonym(s):

(+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide, SNC 80, SNC-80

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Size/SKUAvailabilityPrice
5 mg
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$524.00
25 mg
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$1,890.00

About This Item

Empirical Formula (Hill Notation):
C28H39N3O2
CAS Number:
156727-74-1
Molecular Weight:
449.63
UNSPSC Code:
12352200
PubChem Substance ID:
24278698
NACRES:
NA.77
MDL number:
MFCD00672673
Assay:
≥98% (HPLC)
Form:
solid

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Product Name

SNC80, ≥98% (HPLC), solid

Quality Segment

assay

≥98% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble

SMILES string

CCN(CC)C(=O)c1ccc(cc1)[C@H](N2C[C@H](C)N(CC=C)C[C@H]2C)c3cccc(OC)c3

InChI

1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27?/m0/s1

InChI key

KQWVAUSXZDRQPZ-QNWUEUMSSA-N

Gene Information

human ... OPRD1(4985)
mouse ... Oprd1(18386)
rat ... Oprd1(24613), Oprm1(25601)

Application

Rats were administered SNC80 to study the role of nitric oxide synthase in peripheral antinociception mechanism.5

Biochem/physiol Actions

SNC80 is a δ opioid receptor agonist.
SNC80 is a highly selective agonist of δ opioid receptor but also binds to μ-δ opioid receptor heteromers to produce antinociception in mice.2 It also acts as anti-depressant3, elicits dopamine-related behaviors and enhances behavioral responses to psychostimulants.4

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Show Differences

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This Item
N115T0675E7131
SNC80 ≥98% (HPLC), solid

Sigma-Aldrich

S2812

SNC80

Naltrindole hydrochloride solid

Sigma-Aldrich

N115

Naltrindole hydrochloride

[D-Ala2]-Deltorphin II ≥97% (HPLC)

Sigma-Aldrich

T0675

[D-Ala2]-Deltorphin II

[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)

Sigma-Aldrich

E7131

[D-Ala2, D-Leu5]-Enkephalin acetate salt

description

≥98% (HPLC), solid

description

solid

description

≥97% (HPLC)

description

≥95% (HPLC)

form

solid

form

solid

form

powder

form

-

assay

≥98% (HPLC)

assay

-

assay

≥97% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

solubility

DMSO: soluble

solubility

H2O: 8 mg/mL, methanol: 4.5 mg/mL

solubility

-

solubility

-

color

off-white

color

off-white

color

-

color

-

Gene Information

human ... OPRD1(4985)
mouse ... Oprd1(18386)
rat ... Oprd1(24613), Oprm1(25601)

Gene Information

human ... OPRD1(4985)

Gene Information

human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)
mouse ... Oprd1(18386), Oprm1(18390)
rat ... Oprd1(24613), Oprm1(25601)

Gene Information

human ... OPRD1(4985)
mouse ... OPRD1(18386)
rat ... OPRD1(24613)

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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