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T1001

Thyroglobulin from bovine thyroid

powder, ≥90% (agarose gel electrophoresis)

Synonym(s):

Globulins thyro, Thyractin

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Size/SKUAvailabilityPrice
100 mg
Please contact Customer Service for Availability
R 3 137,00
R 3 074,26
500 mg
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R 12 310,00
R 12 063,80
1 g
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R 21 474,00
R 21 044,52

About This Item

CAS Number:
9010-34-8
UNSPSC Code:
12352202
EC Number:
232-721-3
NACRES:
NA.61
MDL number:
MFCD00132429
Form:
powder
Assay:
≥90% (agarose gel electrophoresis)
Biological source:
bovine thyroid
Mol wt:
~670 kDa

R 3 074,26

List PriceR 3 137,00Save 2%
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biological source

bovine thyroid

Quality Segment

200

assay

≥90% (agarose gel electrophoresis)

form

powder

mol wt

~670 kDa

composition

Iodine, ≥0.20%

nitrogen analysis

13.0-16.0% total

ash

≤4%

solubility

H2O: 20 mg/mL

UniProt accession no.

P01267

storage temp.

−20°C

Gene Information

cow ... TG(280706)

Application

Bovine thyroglobulin was shown to stimulate proliferation in rat thyroid follicular cells as well as in primary porcine thyroid epithelial cells. This effect was mediated through PI3K signaling.
Often used as a carrier protein for the production of antibodies. Its advantage is the large number of tyrosine residues that can be used for conjugation using the diazo reaction.

Biochem/physiol Actions

Bovine thyroglobulin is a large, tetrameric glycoprotein produced in the thyroid gland as a precursor to thyroid hormones. Its large size and absence from plasma under normal conditions makes it very immunogenic and reduces the chance that antibodies to this carrier protein will cross-react with plasma proteins in immunoassays. Haptens may be conjugated to thyroglobulin via accessible secondary amines.
Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by thyroid-stimulating hormone (TSH) from the pituitary. Because its expression is unique to the thyroid, it is a sensitive indicator of recurrence or metastasis of thyroid cancer that has been treated by thyroid ablation.

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This Item
T9145T-113T6830
Thyroglobulin from bovine thyroid powder, ≥90% (agarose gel electrophoresis)

Sigma-Aldrich

T1001

Thyroglobulin from bovine thyroid

Thyroglobulin from bovine thyroid (For Gel Filtration Chromatography)

Sigma-Aldrich

T9145

Thyroglobulin from bovine thyroid

Thyroglobulin solution 10 μg/mL (SigMatrix Serum Diluent), certified reference material, ampule of 1 mL, Cerilliant®

Supelco

T-113

Thyroglobulin solution

Thyroglobulin human

Sigma-Aldrich

T6830

Thyroglobulin human

description

powder, ≥90% (agarose gel electrophoresis)

description

(For Gel Filtration Chromatography)

description

10 μg/mL (SigMatrix Serum Diluent), certified reference material, ampule of 1 mL, Cerilliant®

description

-

biological source

bovine thyroid

biological source

bovine thyroid

biological source

-

biological source

human

assay

≥90% (agarose gel electrophoresis)

assay

-

assay

-

assay

≥95% (SDS-PAGE)

form

powder

form

powder

form

liquid

form

lyophilized solid

mol wt

~670 kDa

mol wt

~670 kDa

mol wt

302607 Da

mol wt

-

solubility

H2O: 20 mg/mL

solubility

-

solubility

-

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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