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T2265

Tetraethylammonium chloride

synthetic (organic), ≥98% (titration), K+ channels blocker, powder

Synonym(s):

TEA chloride

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Size/SKUAvailabilityPrice
25 g

Available to ship TODAY

$73.20
100 g

Available to ship TODAY

$197.00

About This Item

Linear Formula:
(C2H5)4N(Cl)
CAS Number:
Molecular Weight:
165.70
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352107
EC Number:
200-267-5
MDL number:
Beilstein/REAXYS Number:
3563247
Form:
powder
Assay:
≥98% (titration)
Biological source:
synthetic (organic)

$73.20


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Product Name

Tetraethylammonium chloride, ≥98% (titration)

biological source

synthetic (organic)

Quality Segment

assay

≥98% (titration)

form

powder

technique(s)

blocking: suitable

color

white to light yellow

SMILES string

[Cl-].CC[N+](CC)(CC)CC

InChI

1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChI key

YMBCJWGVCUEGHA-UHFFFAOYSA-M

Application

Tetraethylammonium chloride (TEAC) has been used:
  • used for inhibition of peroxynitrite induced relaxation in rat aorta rings
  • as a pharmacological blocker of K+ current and Ca2+ induced K+ current in antennal lobe neurons
  • for the induction of TEAC sensitive currents in cochlear inner hair cells digested with proteolytic enzymes and analyze its properties

Biochem/physiol Actions

Blocks K+ channels; blocks nicotinic acetylcholine neurotransmission by blocking the receptor-mediated K+ currents.
Tetraethylammonium chloride (TEAC) blocks K+ channels non-specifically. In rat aorta rings, tetraethylammonium inhibits relaxation induced by peroxynitrite. It blocks nicotinic acetylcholine neurotransmission by blocking the receptor-mediated K+ currents. TEAC can increase the contractility and mobility of colon and rectum and is a therapeutic option for Hirschsprung′s disease patients. TEAC reduces the inflammatory responses, improves cardiac, vascular and hemodynamic properties during early sepsis in animals. TEAC has cytotoxic and anti-proliferative potential and induces apoptosis in glioma cells by downregulating B-cell lymphoma-2 (Bcl-2) and upregulating Bcl-2 associated X (Bax).

Disclaimer

moisture sensitive, handle under argon

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This Item
8661486616
description

≥98% (titration)

description

BioUltra, Molecular Biology, ≥99.0% (AT)

description

for electrochemical analysis, ≥99.0%

biological source

synthetic (organic)

biological source

-

biological source

-

technique(s)

blocking: suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

-

assay

≥98% (titration)

assay

≥99.0% (AT)

assay

≥99.0%, ≥99.0% (AT)

form

powder

form

powder

form

crystals

Gene Information

human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)

Gene Information

-

Gene Information

-

Quality Level

200

Quality Level

100

Quality Level

100


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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

201.2 °F - closed cup

Flash Point (°C)

94 °C - closed cup

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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