![O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt ≥95%, solid](/deepweb/assets/sigmaaldrich/product/structures/145/804/c567289c-d56d-4488-83ab-a90969f04237/640/c567289c-d56d-4488-83ab-a90969f04237.png)
![Tricyclo[5.2.1.02,6]decanedimethanol diacrylate](/deepweb/assets/sigmaaldrich/product/structures/327/536/0dc81542-b920-47ec-99c1-d064a327a315/640/0dc81542-b920-47ec-99c1-d064a327a315.png)
![4,8-Bis(hydroxymethyl)tricyclo[5.2.1.02,6]decane, mixture of isomers 96%](/deepweb/assets/sigmaaldrich/product/structures/973/006/555dc1f2-c191-4d54-9aea-19fd4c3544a2/640/555dc1f2-c191-4d54-9aea-19fd4c3544a2.png)
We do not have any information about the stability of the product: The product is very labile in solution (1.5 days half-life in tissue culture medium) and is readily hydrolyzed below pH 6.0.
T8543
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt
synthetic (organic), ≥95%, phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor, solid
Synonym(s):
D609
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAY | $295.00 |
25 mg | Check Cart for Availability | $1,190.00 |
About This Item
Empirical Formula (Hill Notation):
C11H15KOS2
CAS Number:
Molecular Weight:
266.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106300
EC Number:
280-379-9
MDL number:
Assay:
≥95%
Form:
solid
$295.00
Available to ship TODAYDetails
Subscriptions are currently unavailable.
Ships Every 4 weeks
Product Name
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate potassium salt, ≥95%, solid
biological source
synthetic (organic)
Quality Segment
assay
≥95%
form
solid
color
off-white to yellow
solubility
H2O: soluble 50 mg/mL, clear to slightly hazy, colorless to faintly yellow, acetone: easily soluble, diethyl ether: insoluble, hydrocarbons: insoluble
SMILES string
[K]SC(=S)OC1CC2CC1C3CCCC23
InChI
1S/C11H16OS2.K/c13-11(14)12-10-5-6-4-9(10)8-3-1-2-7(6)8;/h6-10H,1-5H2,(H,13,14);/q;+1/p-1/t6-,7?,8?,9-,10?;/m1./s1
InChI key
IGULCCCBGBDZKQ-HJPGVBIPSA-M
Application
Biochem/physiol Actions
D609 can block the production of diacylglycerol (DAG) in the cell. D609 functions by inhibiting the phospholipase C-mediated hydrolysis of the phosphate bond present in phosphatidylcholine and other glycerophospholipids.
Phosphatidylcholine-specific phospholipase C (PLC) and HIV-1 inhibitor. Xanthogenate derivative with in vitro anti-tumor activity.
Preparation Note
O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate or D609 is soluble in water at 50 mg/ml and yields a clear to slightly hazy, colorless to light yellow solution. It is also soluble in acetone. However, it is insoluble in ether and hydrocarbons.
Alcoholic solutions should not be prepared due to the possibility of transesterification. The product is very labile in solution (1.5 days half-life in tissue culture medium) and is readily hydrolyzed below pH 6.0. Hence, solutions should be prepared immediately before use and unused solutions must be discarded. For tissue culture preparations, the media should be buffered to pH 6.0-7.5. HEPES buffer must not be used as it renders this product toxic.
Alcoholic solutions should not be prepared due to the possibility of transesterification. The product is very labile in solution (1.5 days half-life in tissue culture medium) and is readily hydrolyzed below pH 6.0. Hence, solutions should be prepared immediately before use and unused solutions must be discarded. For tissue culture preparations, the media should be buffered to pH 6.0-7.5. HEPES buffer must not be used as it renders this product toxic.
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95%, solid | description - | description 96% | description Selective inhibitor of phosphatidylcholine (PC)-specific phospholipase C (Ki = 5-10 µM). |
| form solid | form - | form liquid | form powder |
| assay ≥95% | assay - | assay 96% | assay ≥98% (HPLC) |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| solubility acetone: easily soluble, diethyl ether: insoluble, H2O: soluble 50 mg/mL, clear to slightly hazy, colorless to faintly yellow, hydrocarbons: insoluble | solubility - | solubility - | solubility water: 25 mg/mL, DMSO: 25 mg/mL |
| color off-white to yellow | color - | color - | color off-white |
| biological source synthetic (organic) | biological source - | biological source - | biological source - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
-
Hemos adquirido un vial de 5mg para nuestro laboratorio del IIER-ISCIII. Necesitamos saber en qué debe ser disuelto el producto, ya que se indica que es soluble en agua a 50mg/mL. Es estable? cómo debe almacenarse?
1 answer-
Helpful?
-