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Urea

Name: Urea
Brand: SIGMA

meets USP testing specifications

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:

NH₂CONH₂

CAS Number:

57-13-6

Molecular Weight:

60.06

UNSPSC Code:

12352111

NACRES:

NA.75

PubChem Substance ID:

24900650

EC Number:

200-315-5

Beilstein/REAXYS Number:

635724

MDL number:

MFCD00008022

Assay:

98.0-102.0%

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Properties

Quality Segment

200

agency

USP/NF, meets USP testing specifications

assay

98.0-102.0%

form

solid

dilution

(for analytical testing)

mp

132-135 °C (lit.)

solubility

H₂O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

Description

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

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This Item	BP350	56180	104166
Sigma-Aldrich U4884 Urea	BP350 Urea	Supelco 56180 Urea	SAFC 104166 Urea
description meets USP testing specifications	description British Pharmacopoeia (BP) Reference Standard	description analytical standard	description granulated, EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) cleaning products cosmetics food and beverages forensics and toxicology personal care veterinary	application(s) liquid formulation parenterals pharma/biopharma processes pharmaceutical
Quality Level 200	Quality Level -	Quality Level 100	Quality Level 500
assay 98.0-102.0%	assay -	assay ≥98.5% (HPLC)	assay -
solubility H₂O: soluble 480 g/L at 20 °C	solubility -	solubility H₂O: soluble 480 g/L at 20 °C (completely)	solubility -
form solid	form solid	form -	form granular
density 1.335 g/mL at 25 °C (lit.)	density 1.335 g/mL at 25 °C (lit.)	density 1.335 g/mL at 25 °C (lit.)	density 1.335 g/mL at 25 °C (lit.)

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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