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Monoclonal Anti-Vascular Endothelial Growth Factor antibody produced in mouse

Name: Monoclonal Anti-Vascular Endothelial Growth Factor antibody produced in mouse
Brand: SIGMA
Price: 1130 USD
Availability: InStock

clone 26503, purified immunoglobulin, lyophilized powder

Synonym(s):

Anti-VEGF

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Size/SKU	Availability	Price
0.5 mg	Available to ship TODAYfromMILWAUKEE	$1,130.00

About This Item

UNSPSC Code:

51111800

NACRES:

NA.41

MDL number:

MFCD00282511

Conjugate:

unconjugated

Clone:

26503, monoclonal

Application:

ELISA (c), Neutral, WB

Citations:

$1,130.00

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Properties

Quality Segment

200

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

26503, monoclonal

form

lyophilized powder

species reactivity

primate, human

technique(s)

capture ELISA: 2-8 μg/mL, neutralization: suitable, western blot: 1 μg/mL

isotype

IgG2b

UniProt accession no.

P15692

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... VEGFA(7422), VEGFB(7423), VEGFC(7424)

Description

General description

The antibody will neutralize the biological activity of recombinant human VEGF₁₆₅. It also recognizes VEGF₁₂₁.

Immunogen

purified recombinant Sf21-derived human VEGF (165 aa isoform).

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Monoclonal Anti-Vascular Endothelial Growth Factor antibody produced in mouse was used to block the interaction between VEGF and kinase domain receptor in Calf Pulmonary Aortic Endothelial (CPAE) cells.

Biochem/physiol Actions

The vascular endothelial growth factor family consists of five members, VEGF-A to VEGF-E. They play important roles in important role in embryonic vasculogenesis, angiogenesis and homeostasis. The interaction between VEGFs and their respective receptors results in the activation of MAPK, PI3K, PKC, FAK and Src kinase pathways.

Physical form

Lyophilized from 0.2 um-filtered solution in PBS, pH 7.4 with 5% Trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	V6627	V7259	V1253
Sigma-Aldrich V4758 Monoclonal Anti-Vascular Endothelial Growth Factor antibody produced in mouse	$Anti-Vascular Endothelial Growth Factor antibody produced in goat IgG fraction of antiserum, lyophilized powder$ Sigma-Aldrich V6627 Anti-Vascular Endothelial Growth Factor antibody produced in goat	Sigma-Aldrich V7259 Vascular Endothelial Growth Factor human	Sigma-Aldrich V1253 Anti-Vascular Endothelial Growth Factor antibody produced in goat
description clone 26503, purified immunoglobulin, lyophilized powder	description IgG fraction of antiserum, lyophilized powder	description VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture	description affinity isolated antibody, lyophilized powder
species reactivity primate, human	species reactivity human	species reactivity -	species reactivity mouse
biological source mouse	biological source goat	biological source human	biological source goat
Gene Information human ... VEGFA(7422), VEGFB(7423), VEGFC(7424)	Gene Information human ... VEGFA(7422)	Gene Information human ... VEGFA(7422)	Gene Information mouse ... Vegfa(22339)
conjugate unconjugated	conjugate unconjugated	conjugate -	conjugate unconjugated
antibody form purified immunoglobulin	antibody form IgG fraction of antiserum	antibody form -	antibody form affinity isolated antibody
clone 26503, monoclonal	clone polyclonal	clone -	clone polyclonal

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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