16-246

Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor^™ 488

clone LA1, Upstate^®, from mouse

• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propriedades

• fonte biológica: mouse
• Nível de qualidade: 100
• conjugado: ALEXA FLUOR^™ 488
• forma do anticorpo: purified immunoglobulin
• tipo de produto de anticorpo: primary antibodies
• clone: LA1, monoclonal
• reatividade de espécies: human, mouse, rat
• fabricante/nome comercial: Upstate^®
• técnica(s): immunofluorescence: suitable
• Isotipo: IgG1
• nº de adesão NCBI: NM_005228.3; NM_201282.1; NM_201283.1; NM_201284.1
• nº de adesão UniProt: P00533
• Condições de expedição: wet ice
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... EGFR(1956) ; mouse ... Egfr(13649) ; rat ... Egf(25313)

Descrição

Descrição geral

Included Negative Control: Catalog # 16-240, Alexa Fluor^™ 488-conjugated Normal Mouse IgG.

Inhibits A431 cell growth. Recognizes an antigenic determinant located on the extracellular domain of the receptor.

Imunogênio

Human A431 membrane proteins

Aplicação

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488 is validated for use in IF for the detection of EGFR.

Ações bioquímicas/fisiológicas

external domain of EGF receptor on all human cells. Competes with EGF and TGF-α for binding on human cells. Recognizes both phosphorylated and non-phosphorylated human EGF receptors.

Nota de preparo

1 year at 4°C from date of shipment

Nota de análise

Routinely evaluated by positive immunostaining for the EGF receptor in A431 cells.

Informações legais

ALEXA FLUOR is a trademark of Life Technologies

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Alexa Fluor^™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable