AB16982
Anti-Fas Antibody
CHEMICON®, rabbit polyclonal
Sinônimo(s):
FasL
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Sobre este item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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Estamos aqui para ajudarNome do produto
Anti-Fas Ligand Antibody, Chemicon®, from rabbit
fonte biológica
rabbit
Nível de qualidade
forma do anticorpo
affinity purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
purificado por
affinity chromatography
reatividade de espécies
human, mouse, rat
fabricante/nome comercial
Chemicon®
técnica(s)
ELISA: suitable
western blot: suitable
nº de adesão NCBI
nº de adesão UniProt
Condições de expedição
dry ice
modificação pós-traducional do alvo
unmodified
Informações sobre genes
human ... FAS(355)
1 of 4
Este Item | SAB2105218 | WH0000355M5 | MAB3061 |
|---|---|---|---|
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| antibody form affinity purified immunoglobulin | antibody form affinity isolated antibody | antibody form purified immunoglobulin | antibody form purified immunoglobulin |
| biological source rabbit | biological source rabbit | biological source mouse | biological source mouse |
| Gene Information human ... FAS(355) | Gene Information human ... FAS(355) | Gene Information human ... FAS(355) | Gene Information human ... FAS(355) |
| species reactivity human, mouse, rat | species reactivity human | species reactivity human | species reactivity human |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
Imunogênio
A 13 AA peptide sequence mapping near the C-terminus of human FAS ligand (Mita et al. 1994). This peptide is predicted to be extracellular. The peptide was synthesized with C-terminal Cysteine, coupled to KLH.
Aplicação
Anti-Fas Ligand Antibody detects level of Fas Ligand & has been published & validated for use in ELISA & WB.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Western Blotting: 1:1,000-1:5,000 Rat, mouse and human FASL have 278, 279, and 281 AA residues, respectively (calculated MW 32kDa). Western blot of the oocyte has detected a specific 31kDa band (Hakuno et al. 1996). A 40 kDa FASL has been detected in mouse T cells (Hahne 1995). An alternate detecting reagent, mFAS-Fc (Suda & Nagata 1994) also detected a cell surface protein of about 40 kDa.
ELISA: 0.5-1μg/mL
Optimal working dilutions must be determined by the end user.
ELISA: 0.5-1μg/mL
Optimal working dilutions must be determined by the end user.
Ações bioquímicas/fisiológicas
Human FAS Ligand (FASL). The 13-mer human FASL sequence used for antibody production is 92% (12/13 AA) homologous with rat and mouse FASL. Based upon the sequence homology data, anti-human FASL will likely cross react with the mouse/rat FASL.
forma física
Peptide affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.
Nota de preparo
Maintain frozen at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Outras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informações legais
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
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Prenatal exposure of mice to diethylstilbestrol disrupts T-cell differentiation by regulating Fas/Fas ligand expression through estrogen receptor element and nuclear factor-?B motifs.
Singh, NP; Singh, UP; Nagarkatti, PS; Nagarkatti, M
Journal of Pharmacology and Experimental Therapeutics null
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