Y0002427

Lercanidipine for system suitability CRS

European Pharmacopoeia (EP) Reference Standard

• Sinônimo(s): Lercanidipine hydrochloride, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride
• Fórmula empírica (Notação de Hill): C₃₆H₄₁N₃O₆ · HCl
• Número CAS: 132866-11-6
• Peso molecular: 648.19
• Número MDL: MFCD07773089
• Código UNSPSC: 41116107

Propriedades

• grau: pharmaceutical primary standard
• fabricante/nome comercial: EDQM
• aplicação(ões): pharmaceutical
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O=C(OC)C1=C(C)NC(C)=C(C(OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)=O)C1C4=CC([N+]([O-])=O)=CC=C4.Cl
• InChI: 1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H
• chave InChI: WMFYOYKPJLRMJI-UHFFFAOYSA-N

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Ações bioquímicas/fisiológicas

Lercanidipine hydrochloride is a L-type (Ca_v1.2b) vascular channel antagonist; L-type (Ca_v1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.

Lercanidipine hydrochloride is a L-type (Ca_v1.2b) vascular channel antagonist; L-type (Ca_v1.2a) cardiac channel agonist.

Embalagem

Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit EDQM reference substance catalogue.

Outras notas

EP issued certificate and SDS can be found here.

Sales restrictions may apply.