16-246

Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor^™ 488

clone LA1, Upstate^®, from mouse

• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: ALEXA FLUOR^™ 488
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: LA1, monoclonal
• Speziesreaktivität: human, mouse, rat
• Hersteller/Markenname: Upstate^®
• Methode(n): immunofluorescence: suitable
• Isotyp: IgG1
• NCBI-Hinterlegungsnummer: NM_005228.3; NM_201282.1; NM_201283.1; NM_201284.1
• UniProt-Hinterlegungsnummer: P00533
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... EGFR(1956) ; mouse ... Egfr(13649) ; rat ... Egf(25313)

Beschreibung

Allgemeine Beschreibung

Included Negative Control: Catalog # 16-240, Alexa Fluor^™ 488-conjugated Normal Mouse IgG.

Inhibits A431 cell growth. Recognizes an antigenic determinant located on the extracellular domain of the receptor.

Immunogen

Human A431 membrane proteins

Anwendung

Research Category
Zelluläre Signaltransduktion

Research Sub Category
Wachstumsfaktoren & -rezeptoren

This Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488 is validated for use in IF for the detection of EGFR.

Biochem./physiol. Wirkung

external domain of EGF receptor on all human cells. Competes with EGF and TGF-α for binding on human cells. Recognizes both phosphorylated and non-phosphorylated human EGF receptors.

Angaben zur Herstellung

1 year at 4°C from date of shipment

Hinweis zur Analyse

Routinely evaluated by positive immunostaining for the EGF receptor in A431 cells.

Rechtliche Hinweise

ALEXA FLUOR is a trademark of Life Technologies

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Alexa Fluor^™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable