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Merck

41019

Schmelzpunktstandard 235-237°C

analytical standard

Synonym(e):

Koffein, 1,3,7-Trimethylxanthin

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1 G

CHF 28.10

5 G

CHF 67.60

CHF 28.10


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Über diesen Artikel

Empirische Formel (Hill-System):
C8H10N4O2
CAS-Nummer:
Molekulargewicht:
194.19
Beilstein:
17705
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352210
PubChem Substanz-ID:
NACRES:
NA.24

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Qualität

analytical standard

Qualitätsniveau

Haltbarkeit

limited shelf life, expiry date on the label

mp (Schmelzpunkt)

234-236.5 °C (lit.)
235-237 °C (±0.3°C)

Anwendung(en)

food and beverages
pharmaceutical

Format

neat

SMILES String

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChIKey

RYYVLZVUVIJVGH-UHFFFAOYSA-N

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Dieser Artikel
PHR1095108600675035
format

neat

format

neat

format

neat

format

neat

mp

234-236.5 °C (lit.), 235-237 °C (±0.3°C)

mp

~Approximately 237 °C, 234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

analytical standard

application(s)

food and beverages
pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
food and beverages
personal care
pharmaceutical

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

limited shelf life, expiry date on the certificate and label

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

100

Allgemeine Beschreibung

Melting point standard 235-237 °C, caffeine is useful to calibrate melting point instruments, in the thermodynamic mode of measurement. The value of its melting point is determined with an average of 6 to 12 measurements using a Büchi B-545 instrument that is calibrated against primary standards.

Anwendung

Caffeine melting point standard 235-237 °C finds its use in the characterization of pure chemicals and pharmaceutical compounds.

Leistungsmerkmale und Vorteile

  • Melting point calibration standard traceable to primary standards (LGC, London)
  • Grade: Analytical Standard
  • Standard deviation up to ± 0.3 °C
  • Provided with certificates of analysis and safety data sheet

Sonstige Hinweise

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Jonathan M Hodgson et al.
The American journal of clinical nutrition, 97(5), 943-950 (2013-04-05)
Measures of blood pressure variation have been associated with cardiovascular disease and related outcomes. The regular consumption of black tea can lower blood pressure, but its effects on blood pressure variation have yet to be investigated. We aimed to assess
Louise A Horrigan et al.
Pharmacology & therapeutics, 111(3), 877-892 (2006-03-17)
Caffeine is a member of the methylxanthine family of drugs, and is the most widely consumed behaviourally active substance in the western world. This article is focused on the impact of caffeine on immune function. In this regard, a number
Nicolas Bousette et al.
Journal of cellular physiology, 229(3), 374-383 (2013-09-17)
Calnexin (CNX) is an endoplasmic reticulum (ER) quality control chaperone that has been implicated in ER stress. ER stress is a prominent pathological feature of various pathologic conditions, including cardiovascular diseases. However, the role of CNX and ER stress has
Markus Fehrholz et al.
American journal of physiology. Lung cellular and molecular physiology, 306(1), L101-L109 (2013-10-29)
Factors positively influencing surfactant homeostasis in general and surfactant protein B (SP-B) expression in particular are considered of clinical importance regarding an improvement of lung function in preterm infants. The objective of this study was to identify effects of physiological
Jiangnan Peng et al.
Journal of medicinal chemistry, 53(1), 61-76 (2009-12-19)
Structure-activity relationship studies were carried out by chemical modification of manzamine A (1), 8-hydroxymanzamine A (2), manzamine F (14), and ircinal isolated from the sponge Acanthostrongylophora. The derived analogues were evaluated for antimalarial, antimicrobial, and antineuroinflammatory activities. Several modified products

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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