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Merck

59964

Histamin

analytical standard

Synonym(e):

2-(4-Imidazolyl)-ethylamin

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100 MG

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CHF 60.00

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Über diesen Artikel

Empirische Formel (Hill-System):
C5H9N3
CAS-Nummer:
51-45-6
Molekulargewicht:
111.15
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329758639
EC Number:
200-100-6
Beilstein/REAXYS Number:
2012
MDL number:
MFCD00005210

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Unterstützung erhalten

Produktname

Histamin, analytical standard

InChI key

NTYJJOPFIAHURM-UHFFFAOYSA-N

InChI

1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

SMILES string

NCCc1c[nH]cn1

grade

analytical standard

assay

≥97.0% (TLC)
≥97.0% (anhydrous basis, NT)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤4.0% water

color

white to light yellow

bp

167 °C/0.8 mmHg (lit.)

mp

83-84 °C (lit.)

format

neat

storage temp.

−20°C

Quality Level

100

Gene Information

human ... HRH1(3269)

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1 of 4

Dieser Artikel
H7125Y000177945321
Histamin analytical standard

Supelco

59964

Histamin

Histamin ≥97.0%

Sigma-Aldrich

H7125

Histamin

Histamin European Pharmacopoeia (EP) Reference Standard

Y0001779

Histamin

Ametrin PESTANAL®, analytical standard

Supelco

45321

Ametrin

format

neat

format

-

format

neat

format

neat

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

grade

analytical standard

grade

-

grade

pharmaceutical primary standard

grade

analytical standard

assay

≥97.0% (TLC)

assay

≥97.0%

assay

-

assay

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

limited shelf life, expiry date on the label

impurities

≤4.0% water

impurities

-

impurities

-

impurities

-

Biochem/physiol Actions

Endogener H1- und H2-Histaminrezeptoragonist; aktiviert die Stickstoffoxid-Synthase; potenter Vasodilatator.
Endogener H1- und H2-Histaminrezeptoragonist; die H1-Aktivierung mobilisiert Ca2+; die H2-Aktivierung stimuliert die Adenylatcyclase-Aktivität in Neuronen; aktiviert die Stickstoffoxid-Synthase; potenter Vasodilatator.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCN3647
BCCL5303
BCCK6304
BCCK1125
BCCJ2322

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Suche nach COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

P J Turner et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 25(7), 657-661 (2014-10-10)
Most children with egg allergy tolerate egg in baked foods, such as cake, but tolerance cannot be predicted with conventional allergy testing. We hypothesized that the skin prick test (SPT) wheal to unprocessed raw egg might predict tolerance of baked
Ye Zhang et al.
Investigative ophthalmology & visual science, 56(1), 563-570 (2015-01-13)
We estimate and compare change in iris cross-sectional area (IA) after physiologic and pharmacologic mydriasis in subjects with different dominant mechanisms for primary angle closure. Anterior segment optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were
Andrea Strasser et al.
Trends in pharmacological sciences, 34(1), 13-32 (2012-12-12)
Histamine is a biogenic amine that exerts its biological effects as a neurotransmitter and local mediator via four histamine receptor (HR) subtypes (H(x)Rs) - H(1)R, H(2)R, H(3)R, and H(4)R - belonging to the superfamily of G-protein-coupled receptors (GPCRs). All four
W Tang et al.
Oncogene, 33(20), 2629-2638 (2013-06-12)
Recent studies suggested that cancer stem cells (CSCs) are capable of differentiating into endothelial cells and tumor endothelium may be derived from CSCs. But the mechanism remains unclear. We showed that vascular endothelial growth factor (VEGF) induced the expression of
Katsuya Nagai et al.
Amino acids, 43(1), 97-109 (2012-03-01)
L-carnosine (β-alanyl-L-histidine; CAR) is synthesized in mammalian skeletal muscle. Although the physiological roles of CAR have not yet been clarified, there is evidence that the release of CAR from skeletal muscle during physical exercise affects autonomic neurotransmission and physiological functions.
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Questions

1–4 of 4 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. How should Product 59964, Histamine analytical standard , be dissolved and what is the solution stability, where the solution should be stored?

    1 answer

    1. No direct solution stability studies have been performed on this product. It is expected that the compound can be reconstituted in water and stored at -20°C. Information with related histamine products indicates solubility at 100 mg/mL in water. Please keep in mind that the solvent used for reconstitution may vary based on the application.

      Helpful?

  4. 59964 histamine for oral consumption and storage temperature

    1 answer

    1. This product is not suitable for oral consumption. Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.

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