G5146

D-(+)-Glukose

Hybri-Max^™, powder, BioReagent, suitable for hybridoma

• Synonym(e): Dextrose
• Empirische Formel (Hill-System): C₆H₁₂O₆
• CAS-Nummer: 50-99-7
• Molekulargewicht: 180.16
• Beilstein: 1724615
• EG-Nummer: 200-075-1
• MDL-Nummer: MFCD00063774
• UNSPSC-Code: 12352201
• PubChem Substanz-ID: 24895199
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: maize
• Qualitätsniveau: 200
• Qualität: Hybri-Max^™
• Produktlinie: BioReagent
• Assay: ≥99.5%
• Form: powder
• Methode(n): cell culture | hybridoma: suitable
• Verunreinigungen: endotoxin, tested
• mp (Schmelzpunkt): 150-152 °C (lit.)
• Löslichkeit: H₂O: 2g + 15 mL (Tested)
• SMILES String: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• InChIKey: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• Angaben zum Gen: human ... PYGM(5837)

Beschreibung

Allgemeine Beschreibung

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively.[1] The PYGM gene is mapped to human chromosome 11q13.1.[2]

Anwendung

D-(+)-Glucose has been used in cell engineering.[3] It has also been used to perform oral glucose tolerance test.[4]

Biochem./physiol. Wirkung

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia.[1] Mutation in PYGM leads to McArdle disease, a glycogen storage disorder.[5] The PYGM gene is significantly associated with energy production.[6]

Angaben zur Herstellung

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Rechtliche Hinweise

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)