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Merck

T8657

Trichloressigsäure

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

Synonym(e):

TCA

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Größe auswählen

250 G

CHF 114.00

500 G

CHF 191.00

1 KG

CHF 284.00

CHF 114.00


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Über diesen Artikel

Lineare Formel:
Cl3CCOOH
CAS-Nummer:
Molekulargewicht:
163.39
Beilstein:
970119
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41105319
PubChem Substanz-ID:
NACRES:
NB.22

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Qualität

electrophoresis grade

Qualitätsniveau

Dampfdichte

<1 (vs air)

Dampfdruck

1 mmHg ( 51 °C)

Assay

≥99%

Form

powder or flakes (or crystals)

Methode(n)

electrophoresis: suitable

Trübung

≤3 NTU (1 g/ml)

Brechungsindex

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp (Schmelzpunkt)

54-58 °C (lit.)

Löslichkeit

water: 1 g/mL, clear, colorless

Dichte

1.62 g/mL at 25 °C (lit.)

Anionenspuren

chloride (Cl-): ≤0.001%
nitrate (NO3-): ≤0.002%
phosphate (PO43-): ≤5 ppm
sulfate (SO42-): ≤0.02%

Kationenspuren

Fe: ≤0.0005%
heavy metals (as Pb): ≤0.002%

Eignung

suitable for fixing solution (for IEF and PAGE gels)

Anwendung(en)

cell analysis

Lagertemp.

2-8°C

SMILES String

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChIKey

YNJBWRMUSHSURL-UHFFFAOYSA-N

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1 of 4

Dieser Artikel
T48858.22342T0699
assay

≥99%

assay

≥99.0% (titration)

assay

≥98% (acidimetric)

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder or flakes (or crystals)

form

powder or crystals

form

solid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

-

solubility

water: 1 g/mL, clear, colorless

solubility

H2O: 1 g/10 mL

solubility

1300 g/L

solubility

-

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

-

vapor density

-

Allgemeine Beschreibung

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material.[1] It is a novel reagent used in clinical laboratories for deproteinization of body fluids.[2] In addition, TCA is also used in the treatment of genital warts[3] and acne scars.[4]

Anwendung

Traditionell zur Fällung von Proteinen verwendet. Zur Bestimmung der Proteinkonzentration durch quantitative Fällung. Zum Entkalken und als Fixationsmittel in der Mikroskopie verwendet.
Trichloroacetic acid has been used:
  • for hydrolysis of DNA isolated from the cell[5]
  • for precipitation of glutathione isolated from seminal plasma[6]
  • as a fixative in microscopy[7]

Piktogramme

CorrosionEnvironment

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

Lagerklassenschlüssel

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

Flammpunkt (°F)

>235.4 °F - closed cup

Flammpunkt (°C)

> 113 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

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Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method
Lee J, et al.
Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [Et Al.], 28(11), 1017-1021 (2002)
Quantitation of DNA fragmentation with diphenylamine
Boraschi D and Maurizi G
Apoptosis-a laboratory manual of experimental methods, 153-161 (1998)
Atmospheric pressure pulsed plasma induces cell death in photosynthetic organs via intracellularly generated ROS
Seol Y, et al.
Scientific reports, 7(1), 589-589 (2017)
Determination of total protein in spinal fluid with sulphosalicylic acid and trichloroacetic acid
Meulemans O
Clinica Chimica Acta; International Journal of Clinical Chemistry, 5(5), 757-761 (1960)
Teratogenic activity of trichloroacetic acid in the rat
Smith MK, et al.
Teratology, 40(5), 445-451 (1989)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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