16-246

Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor^™ 488

clone LA1, Upstate^®, from mouse

• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Conjugué: ALEXA FLUOR^™ 488
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: LA1, monoclonal
• Espèces réactives: human, mouse, rat
• Fabricant/nom de marque: Upstate^®
• Technique(s): immunofluorescence: suitable
• Isotype: IgG1
• Numéro d'accès NCBI: NM_005228.3; NM_201282.1; NM_201283.1; NM_201284.1
• Numéro d'accès UniProt: P00533
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... EGFR(1956) ; mouse ... Egfr(13649) ; rat ... Egf(25313)

Description

Description générale

Included Negative Control: Catalog # 16-240, Alexa Fluor^™ 488-conjugated Normal Mouse IgG.

Inhibits A431 cell growth. Recognizes an antigenic determinant located on the extracellular domain of the receptor.

Immunogène

Human A431 membrane proteins

Application

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488 is validated for use in IF for the detection of EGFR.

Actions biochimiques/physiologiques

external domain of EGF receptor on all human cells. Competes with EGF and TGF-α for binding on human cells. Recognizes both phosphorylated and non-phosphorylated human EGF receptors.

Notes préparatoires

1 year at 4°C from date of shipment

Remarque sur l'analyse

Routinely evaluated by positive immunostaining for the EGF receptor in A431 cells.

Informations légales

ALEXA FLUOR is a trademark of Life Technologies

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Alexa Fluor^™ is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable