Y0002427

Lercanidipine hydrochloride

European Pharmacopoeia (EP) Reference Standard

• Synonyme(s) : Lercanidipine hydrochloride, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride
• Formule empirique (notation de Hill) : C₃₆H₄₁N₃O₆ · HCl
• Numéro CAS: 132866-11-6
• Poids moléculaire : 648.19
• Numéro MDL: MFCD07773089
• Code UNSPSC : 41116107

Propriétés

• Qualité: pharmaceutical primary standard
• Fabricant/nom de marque: EDQM
• Application(s): pharmaceutical
• Température de stockage: 2-8°C
• Chaîne SMILES: O=C(OC)C1=C(C)NC(C)=C(C(OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)=O)C1C4=CC([N+]([O-])=O)=CC=C4.Cl
• InChI: 1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H
• Clé InChI: WMFYOYKPJLRMJI-UHFFFAOYSA-N

Description

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Actions biochimiques/physiologiques

Lercanidipine hydrochloride is a L-type (Ca_v1.2b) vascular channel antagonist; L-type (Ca_v1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.

Lercanidipine hydrochloride is a L-type (Ca_v1.2b) vascular channel antagonist; L-type (Ca_v1.2a) cardiac channel agonist.

Conditionnement

Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit EDQM reference substance catalogue.

Autres remarques

EP issued certificate and SDS can be found here.

Sales restrictions may apply.