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Merck

1043003

USP

Acide ascorbique

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Acide L-ascorbique, Acide L-thréoascorbique, Facteur anti-scorbut, Vitamine C

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1 G

427,00 €

427,00 €


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A propos de cet article

Formule empirique (notation de Hill) :
C6H8O6
Numéro CAS:
Poids moléculaire :
176.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:

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Nom du produit

Acide ascorbique, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

grade

pharmaceutical primary standard

API family

ascorbic acid

form

solid

manufacturer/tradename

USP

technique(s)

HPLC: suitable

mp

190-194 °C (dec.)

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

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Cet article
A1300000A221857803
grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

-

grade

certified reference material, TraceCERT®

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

food and beverages

format

neat

format

neat

format

-

format

neat

API family

ascorbic acid

API family

ascorbic acid

API family

-

API family

-

technique(s)

HPLC: suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Analysis Note

Ces produits ne doivent être utilisés qu′aux fins de tests et de dosages. Ils ne sont pas destinés à être administrés à l′homme ou à l′animal et ne peuvent en aucun cas être utilisés pour diagnostiquer, traiter ou guérir une maladie, quelle qu′elle soit.

Application

Étalon de référence USP de l'acide ascorbique, destiné aux essais et tests de qualité spécifiés dans les recueils de la pharmacopée américaine. Produit aussi destiné à être utilisé avec les monographies de l'USP suivantes :
  • Acide ascorbique, comprimés
  • Acide ascorbique, pour préparation injectable
  • Acide ascorbique, gel à mâcher
  • Acide ascorbique, solution officinale par voie orale
  • Ascorbate de sodium
  • Ascorbate de calcium

Other Notes

Des restrictions peuvent s′appliquer à la vente de ce produit.
This product is part of USP Biologics Program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

General description

Ascorbic acid, commonly known as vitamin C, is a water-soluble vitamin with antioxidant properties. In pharmaceutical and food industries, ascorbic acid is used as an antioxidant to prevent oxidation and spoilage. The USP Ascorbic Acid standard ensures the quality and potency of ascorbic acid in various formulations.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Ascorbic Acid Chewable Gels
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(4), 4765-4765 (2019)
W Lee et al.
Clinical chemistry, 28(10), 2165-2169 (1982-10-01)
Measurements of ascorbic acid concentration in leukocytes by "high-performance" liquid chromatography (HPLC) provides better nutritional assessment, leading to better management, particularly of presymptomatic and critically ill patients. This procedure includes a simple, reproducible cell-separation technique that requires no more than
Glutathione
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(3), 5054-5054 (2020)
Ascorbic Acid Compounded Oral Solution
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(4), 2626-2626 (2020)
Ascorbic Acid Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(6), 383-383 (2022)

Questions

1–2 sur 2 questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 réponse
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 réponse
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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