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Merck

14-679-M

HIPK1 Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555. For use in Kinase Assays.

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10 μG

468,00 €

14-679M

3.480,00 €

468,00 €

Spedizione prevista il27 gennaio 2026Dettagli

Informazioni su questo articolo

Codice UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.32

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Origine biologica

human

Livello qualitativo

100
300

Ricombinante

expressed in baculovirus infected Sf21 cells

PM

Mw 49.6 kDa

Produttore/marchio commerciale

Upstate®

tecniche

activity assay: suitable (kinase)

N° accesso NCBI

NM_152696.3
NM_181358.1
NM_198268.1
NM_198269.1

N° accesso UniProt

Q86Z02

Informazioni sul gene

human ... HIPK1(204851)

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Questo articolo
14-623-M14-684-M14-656-M
HIPK1 Protein, active, 10 µg Active, N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555. For use in Kinase Assays.

Sigma-Aldrich

14-679-M

HIPK1 Protein, active, 10 µg

HIPK2 Protein, active, 10 µg Active, N-terminal His6-tagged, recombinant, human HIPK2, amino acids 165-564, for use in Kinase Assays.

Sigma-Aldrich

14-623-M

HIPK2 Protein, active, 10 µg

IRAK1 Protein, active, 10 µg Active, N-terminal 6His-tagged, recombinant, human IRAK1 amino acids 194-end. For use in Kinase Assays.

Sigma-Aldrich

14-684-M

IRAK1 Protein, active, 10 µg

LIM Kinase 1 Protein, active, 10 µg Active, N-terminal 6His-tagged, recombinant, human LIM Kinase 1, amino acids 285-638, for use in Kinase Assays.

Sigma-Aldrich

14-656-M

LIM Kinase 1 Protein, active, 10 µg

recombinant

expressed in baculovirus infected Sf21 cells

recombinant

expressed in baculovirus infected Sf21 cells

recombinant

expressed in baculovirus infected Sf21 cells

recombinant

expressed in baculovirus infected Sf21 cells

biological source

human

biological source

human

biological source

human

biological source

human

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

mol wt

Mw 49.6 kDa

mol wt

Mw 49.6 kDa

mol wt

Mw 59.7 kDa

mol wt

Mw 41.2 kDa

Gene Information

human ... HIPK1(204851)

Gene Information

human ... HIPK2(28996)

Gene Information

-

Gene Information

human ... LIMK1(3984)

UniProt accession no.

Q86Z02

UniProt accession no.

Q9H2X6

UniProt accession no.

P51617

UniProt accession no.

P53667

Descrizione generale

N-terminal 6His-tagged, recombinant, human HIPK1, amino acids 158-555.
Product Source: HIPK1 expressed by baculovirus in Sf21 cells.

Applicazioni

Research Category
Metabolism
Research Sub Category
Obesity

Metabolic Disorders

Azioni biochim/fisiol

Protein Target: HIPK1
Target Sub-Family: CMGC

Stato fisico

Ni2+/NTA-agarose

Nota sulla preparazione

6 months at -70°C from date of shipment

Risultati analitici

routinely evaluated by phosphorylation of MBP (13-104).

Altre note

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H317

Classi di pericolo

Skin Sens. 1

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Jae J Song et al.
The Journal of biological chemistry, 278(47), 47245-47252 (2003-09-12)
Overexpression of JNK binding domain inhibited glucose deprivation-induced JNK1 activation, relocalization of Daxx from the nucleus to the cytoplasm, and apoptosis signal-regulating kinase 1 (ASK1) oligomerization in human prostate adenocarcinoma DU-145 cells. However, SB203580, a p38 inhibitor, did not prevent
Jeffrey A Ecsedy et al.
Molecular and cellular biology, 23(3), 950-960 (2003-01-17)
We describe an interaction between homeodomain-interacting protein kinase 1 (HIPK1) and Daxx, two transcriptional regulators important in transducing growth-regulatory signals. We demonstrate that HIPK1 is ubiquitously expressed in mice and humans and localizes predominantly to the nucleus. Daxx normally resides
Y H Kim et al.
The Journal of biological chemistry, 273(40), 25875-25879 (1998-09-25)
A novel family of cofactors that differentially interact with homeoproteins have been identified via a yeast two-hybrid screen. The proteins contain a conserved protein kinase domain that is separated from a domain that interacts with homeoproteins and hence are termed

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Recensioni

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