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A1300000

Acido L-ascorbico

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Acido L-treoascorbico, Fattore antiscorbuto, Vitamina C

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70 MG

183,00 €

183,00 €


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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C6H8O6
Numero CAS:
Peso molecolare:
176.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:

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Nome del prodotto

Acido L-ascorbico, European Pharmacopoeia (EP) Reference Standard

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP Reference standard

API family

ascorbic acid

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

190-194 °C (dec.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Questo articolo
PHR1008A221857803
Acido L-ascorbico European Pharmacopoeia (EP) Reference Standard

A1300000

Acido L-ascorbico

Acido L-ascorbico Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1008

Acido L-ascorbico

Acido L-ascorbico certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

57803

Acido L-ascorbico

application(s)

pharmaceutical (small molecule)

application(s)

food and beverages

application(s)

pharmaceutical (small molecule)

application(s)

food and beverages

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

form

solid

form

solid

form

solid

form

solid

format

neat

format

neat

format

-

format

neat

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

certified reference material, TraceCERT®

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

20-25°C

Application

Ascorbic EP reference standard, intended for use only as specifically prescribed in the European Pharmacopoeia. Also used for the determination of the analyte in pharmaceutical formulations by chromatography[1][2] and spectrophotometric[3] techniques.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

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Spectrophotometric determination of L-ascorbic acid in pharmaceuticals
Szpikowska-Sroka B and Poledniok J
Journal of Analytical Chemistry, 66(10), 941-941 (2011)
Reversed-phase ion-pair HPLC determination of some water-soluble vitamins in pharmaceuticals
Ivanovic D, et al.
Journal of Pharmaceutical and Biomedical Analysis, 18(6), 999-1004 (1999)
Ascorbic acid
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 18(6), 6868-6869 (2019)
Vitamin C: One compound, several uses. Advances for delivery, efficiency and stability
Carita AC, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 31(2), 102117-102117 (2019)
First bioarchaeological evidence of probable scurvy in Southeast Asia: multifactorial etiologies of vitamin C deficiency in a tropical environment
Halcrow SE, et al.
International Journal of Paleopathology, 5(1), 63-71 (2014)

Domande

1–3 di 3 domande  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

  3. I want to ask if the ascorbic acid, product A1300000 is delivered as powder and how many grams are in one bottle? Could you send me an example of a CoA? Has it be dried before usage as we would like to use it as standard for titer determination of Iodine?

    1 risposta
    1. This is a product of the European Pharmacopoeia. Each vial contains 70 mg of Ascorbic acid in powder form. Please visit the European Pharmacopeia website for more information and download the leaflet: https://crs.edqm.eu/db/4DCGI/leaflet?leaflet=A1300000_5.pdf

      Utile?

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