P9159

Piperidine-4-sulfonic acid

Name: Piperidine-4-sulfonic acid
Brand: SIGMA
Price: 133.45 EUR

Sinonimo/i:

P4S

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25 MG

133,45 €

250 MG

651,10 €

133,45 €

Prezzo di listino157,00 €Risparmia il 15%

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₅H₁₁NO₃S

Numero CAS:

72450-62-5

Peso molecolare:

165.21

NACRES:

NA.77

PubChem Substance ID:

24278165

UNSPSC Code:

12352106

MDL number:

MFCD00055097

Documenti fondamentali

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InChI

1S/C5H11NO3S/c7-10(8,9)5-1-3-6-4-2-5/h5-6H,1-4H2,(H,7,8,9)

SMILES string

OS(=O)(=O)C1CCNCC1

InChI key

UGBJGGRINDTHIH-UHFFFAOYSA-N

form

powder

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Questo articolo	D1262	P9625	D2531
Sigma-Aldrich P9159 Piperidine-4-sulfonic acid	Sigma-Aldrich D1262 P¹,P⁴-Di(adenosine-5′) tetraphosphate ammonium salt	Sigma-Aldrich P9625 Phenazine methosulfate	Sigma-Aldrich D2531 Dextromethorphan hydrobromide monohydrate
form powder	form powder	form powder	form powder
Gene Information human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)	Gene Information human ... PLD1(5337), PLD2(5338), PLD3(23646), PLD4(122618), PLD5(200150)	Gene Information -	Gene Information human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), SIGMAR1(10280)

Biochem/physiol Actions

GABA_A receptor agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number

0000379482

0000300095

0000234465

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Identifying agonistic and antagonistic mechanisms operative at the GABA receptor.

E Galvez-Ruano et al.

Journal of neuroscience research, 42(5), 666-673 (1995-12-01)

Based on our molecular modeling investigations of the glycinergic receptor, we expanded our studies to similarly investigate the GABAergic receptor. New data suggest there may exist a slightly different agonistic mechanism for the molecules described herein as compared to glycine.

Eighteen-year follow-up cohort study on hepatitis B and C virus infections related long-term prognosis among hemodialysis patients in Hiroshima.

Ko Ko et al.

Journal of medical virology (2020-06-25)

This study aimed to investigate the prevalence trend of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and their genotype distribution among hemodialysis patients, determining their long-term prognosis and the risk factors to the mortality. This cohort study

The pre-M1 segment of the alpha1 subunit is a transduction element in the activation of the GABAA receptor.

Angelo Keramidas et al.

The Journal of physiology, 575(Pt 1), 11-22 (2006-06-10)

The binding of the neurotransmitter GABA induces conformational changes in the GABAA receptor (GABAAR), leading to the opening of a gate that controls ion permeation through an integral transmembrane pore. A number of structural elements within each subunit, located near

Differences in agonist/antagonist binding affinity and receptor transduction using recombinant human gamma-aminobutyric acid type A receptors.

B Ebert et al.

Molecular pharmacology, 52(6), 1150-1156 (1997-12-16)

Using human gamma-aminobutyric acid type A (GABAA) receptor subunit combinations, expressed in cell lines and Xenopus laevis oocytes, the pharmacology of a number of ligands interacting directly with the GABA recognition site has been studied in [3H]muscimol binding and electrophysiologically.

Role of the fastigial nucleus in generalized seizures as demonstrated by GABA agonist microinjections.

J W Miller et al.

Epilepsia, 34(6), 973-978 (1993-11-01)

The cerebellum is electrically and metabolically active during seizures. Numerous studies have also shown that cerebellar electrical stimulation and lesions of the cerebellar cortex or nuclei influence seizure threshold, but there are significant contradictions, with different effects observed even in

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