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Merck

1375502

USP

Mebendazole

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, Mebendazol, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

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200 MG

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C16H13N3O3
Numero CAS:
Peso molecolare:
295.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
759809

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Nome del prodotto

Mebendazole, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

mebendazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

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Mebendazole analytical standard, ≥98% (HPLC)

Supelco

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manufacturer/tradename

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EDQM

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

analytical standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical small molecule

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

format

neat

format

-

format

neat

API family

mebendazole

API family

mebendazole

API family

mebendazole

API family

-

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Mebendazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Mebendazole Tablets
  • Mebendazole Oral Suspension
  • Fenbendazole
  • Pimozide Tablets
  • Pimozide

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3


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T Inaoka et al.
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 62(1), 54-67 (1987-01-01)
The effects of the mebendazole, albendazole and ivermectin on secondary multilocular echinococcosis in Chinese hamsters infected with intraperitoneal inoculation of protoscolices and in rats infected with transportal inoculation of protoscolices were investigated. A reduction in weight of the hydatids greater
Mebendazole and related anthelmintics.
H Van den Bossche et al.
Advances in pharmacology and chemotherapy, 19, 67-128 (1982-01-01)
A Bennett et al.
Parasitology today (Personal ed.), 16(2), 71-74 (2000-02-01)
The widespread use of mebendazole and albendazole for treating intestinal nematode infections in human populations is raising concerns that careful monitoring pro- cedures should be in place to identify any emergence of drug resistance. In this article, Andy Bennett and
Olga Staudacher et al.
Tropical medicine & international health : TM & IH, 19(7), 812-824 (2014-04-23)
Preventive chemotherapy of schoolchildren against soil-transmitted helminths (STHs) is widely implemented in Rwanda. However, data on its actual efficacy are lacking. We assessed prevalence, associated factors and manifestation of STH infection among schoolchildren in southern highland Rwanda as well as
Cong-Shan Liu et al.
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 27(6), 513-519 (2010-03-18)
Mebendazole is currently used in the treatment of hydatid disease. Its poor absorption from the gastrointestinal tract and low bioavailability aroused further research on new formulations of mebendazole to increase the bioavailability and improve the therapeutic efficacy. This review summarizes

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