NA29
Anti-p16 (Ab-1) Mouse mAb (DCS-50.1/H4)
liquid, clone DCS-50.1/H4, Calbiochem®
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この商品について
UNSPSCコード:
12352203
NACRES:
NA.43
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由来生物
mouse
品質水準
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
DCS-50.1/H4, monoclonal
フォーム
liquid
含みます
≤0.1% sodium azide as preservative
交差性
human
メーカー／製品名
Calbiochem®
保管条件
do not freeze
dilution
(Immunoblotting (0.5-5 µg/mL, )
アイソタイプ
IgG1
輸送温度
wet ice
保管温度
2-8°C
ターゲットの翻訳後修飾
unmodified
1 of 4
当該品目 | CC12 | OP46 | NA03 |
|---|---|---|---|
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| antibody form purified antibody | antibody form purified antibody | antibody form purified antibody | antibody form purified antibody |
| species reactivity human | species reactivity human, mouse, rat | species reactivity human | species reactivity rat, yeast, mouse, human, zebrafish |
| clone DCS-50.1/H4, monoclonal | clone DCS-6, monoclonal | clone IF2, monoclonal | clone PC10, monoclonal |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
| isotype IgG1 | isotype IgG2a | isotype IgG2b | isotype IgG2a |
詳細
Purified mouse monoclonal antibody generated by immunizing BALB/c mice with the specified immunogen and fusing splenocytes with NS-2 mouse myeloma cells. Recognizes the ~16 kDa p16 protein.
Recognizes the ~16 kDa p16 protein in Saos-2 cells and bladder tissue. Sold under license of U.S. Patent 6,482,929. Sold under license of U.S. Patent 5,843,756, 6,090,578, and corresponding patents.
This Anti-p16 (Ab-1) Mouse mAb (DCS-50.1/H4) is validated for use in Immunoblotting for the detection of p16 (Ab-1).
免疫原
Human
recombinant, human p16
アプリケーション
Immunoblotting (0.5-5 µg/ml, see application references)
包装
Please refer to vial label for lot-specific concentration.
物理的形状
In 0.05 M sodium phosphate buffer, 0.2% gelatin pH 7.5.
アナリシスノート
Negative Control
U2OS cells
U2OS cells
Positive Control
Saos-2 cells or bladder tissue
Saos-2 cells or bladder tissue
その他情報
Does not cross-react with the closely related p15 protein. Antibody should be titrated for optimal results in individual systems.
Koh, J., et al. 1995. Nature375, 506.
Lukas, J., et al. 1995. Nature375, 503.
Cheng, J.Q., et al. 1994. Cancer Res.54, 5547.
Jen, J., et al. 1994. Cancer Res.54, 6353.
Kamb, A., et al. 1994 Science264, 436.
Nobori, T., Miura, K., et al. 1994. Nature368, 753.
Okamoto, A., Demetrick, D.J., et al. 1994. Proc. Natl. Acad. Sci. USA91, 11045.
Serrano, M., et al. 1993. Nature366 704.
Lukas, J., et al. 1995. Nature375, 503.
Cheng, J.Q., et al. 1994. Cancer Res.54, 5547.
Jen, J., et al. 1994. Cancer Res.54, 6353.
Kamb, A., et al. 1994 Science264, 436.
Nobori, T., Miura, K., et al. 1994. Nature368, 753.
Okamoto, A., Demetrick, D.J., et al. 1994. Proc. Natl. Acad. Sci. USA91, 11045.
Serrano, M., et al. 1993. Nature366 704.
法的情報
Sold under license of U.S. Patents 5,843,756, 6,090,578 and corresponding patents.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Toxicity: Standard Handling (A)
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
NA29-100UG:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Goro Sashida et al.
Molecular and cellular biology, 29(13), 3687-3699 (2009-04-22)
Several ETS transcription factors, including ELF4/MEF, can function as oncogenes in murine cancer models and are overexpressed in human cancer. We found that Elf4/Mef activates Mdm2 expression; thus, lack of or knockdown of Elf4/Mef reduces Mdm2 levels in mouse embryonic
Noriyasu Usami et al.
Oncogene, 22(39), 7923-7930 (2003-09-13)
We have found that a malignant mesothelioma cell line, NCI-H28, had a chromosome 3p21.3 homozygous deletion containing the beta-catenin gene (CTNNB1), which suggested that the deletion of beta-catenin might have a growth advantage in the development of this tumor. To
Frederick Y Wu et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(16), 10683-10688 (2002-07-30)
Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic DNA virus that causes Kaposi sarcoma and AIDS-related primary effusion lymphoma (PEL). Here we show that KSHV lytic cycle replication in PEL cells induces G(1) cell cycle arrest, presumably to facilitate the progression
Masashi Narita et al.
Cell, 113(6), 703-716 (2003-06-18)
Cellular senescence is an extremely stable form of cell cycle arrest that limits the proliferation of damaged cells and may act as a natural barrier to cancer progression. In this study, we describe a distinct heterochromatic structure that accumulates in
Jeffrey T Irelan et al.
PloS one, 4(4), e5067-e5067 (2009-04-03)
The CDKN2A locus encodes two important tumor suppressors, INK4a and ARF, which respond to oncogenic stresses by inducing cellular senescence. We conducted a genome-scale cDNA overexpression screen using a reporter containing INK4a regulatory sequences to identify novel transcriptional activators of
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