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この商品について
実験式(ヒル表記法):
C10H18O2
CAS番号:
分子量:
170.25
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1721990
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製品名
cis-2-Decenoic acid, ≥95.0% (HPLC)
SMILES string
CCCCCCC\C=C/C(O)=O
InChI key
WXBXVVIUZANZAU-HJWRWDBZSA-N
InChI
1S/C10H18O2/c1-2-3-4-5-6-7-8-9-10(11)12/h8-9H,2-7H2,1H3,(H,11,12)/b9-8-
assay
≥95.0% (HPLC)
95.0-105.0% (T)
form
liquid
functional group
carboxylic acid
lipid type
unsaturated FAs
storage temp.
−20°C
Quality Level
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関連するカテゴリー
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当該品目 | C1875 | I4386 | 75447 |
|---|---|---|---|
| assay ≥95.0% (HPLC), 95.0-105.0% (T) | assay ≥98.0% | assay ≥98.0% (T) | assay ≥95.0% (HPLC), ≥97.0% (T) |
| functional group carboxylic acid | functional group carboxylic acid | functional group - | functional group - |
| storage temp. −20°C | storage temp. room temp | storage temp. −20°C | storage temp. 2-8°C |
| form liquid | form crystals | form powder or flakes | form powder |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| lipid type unsaturated FAs | lipid type saturated FAs | lipid type - | lipid type saturated FAs |
Application
Biochem/physiol Actions
cis-2-Decenoic acid is a fatty acid messenger (signaling molecule) produced by Pseudomonas aeruginosa.[3] It possesses anti-biofilm property[3] and converts most of the cells to planktonic (free-swimming) phenotype.[4] cis-2-Decenoic acid retains the susceptibility of the bacteria towards antimicrobial agents. It does not exhibit any toxicity towards human cells and thus, might be used for treating biofilm-associated infections. cis-2-Decenoic acid is considered active even in nano-molar ranges.[3] It mediates the transition of dormant P. aeruginosa and Escherichia coli to their biologically active state without affecting the number of cells. cis-2-Decenoic acid is effective against E. coli and Klebsiella pneumoniae mixed-species biofilms when used along with antimicrobial agents.[4]
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2
保管分類
10 - Combustible liquids
wgk
WGK 1
Azadeh Rahmani-Badi et al.
Archives of oral biology, 60(11), 1655-1661 (2015-09-10)
To investigate the ability of cis-2-decenoic acid (C2DA) to induce dispersion in single-species biofilms formed by Streptococcus mutans and Candida albicans, as well as to remove their bacterial-fungal dual-species biofilms when combined with low concentrations of chlorhexidine (CHX). For biofilm
Majed Alrobaian et al.
Molecules (Basel, Switzerland), 24(10) (2019-05-28)
Two series of novel 5-arylazo-3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galacto pyranosyloxy) pyridines and 3-cyano-2-(2″,3″,4″,6″-tetra-O-acetyl-β-d-galactopyranosyloxy) pyridines were synthesized in high yields utilizing a microwave-assisted synthesis tool guided by the principles of green chemistry. The chemical structures of the new substances were confirmed on the basis of
Han-Shin Kim et al.
Biotechnology and bioengineering, 118(1), 82-93 (2020-09-04)
Bacterial biofilm formation causes serious problems in various fields of medical, clinical, and industrial settings. Antibiotics and biocide treatments are typical methods used to remove bacterial biofilms, but biofilms are difficult to remove effectively from surfaces due to their increased
Martha María Juárez-Rodríguez et al.
Frontiers in cellular and infection microbiology, 10, 597517-597517 (2021-02-16)
Blocking virulence is a promising alternative to counteract Pseudomonas aeruginosa infections. In this regard, the phenomenon of cell-cell communication by quorum sensing (QS) is an important anti-virulence target. In this field, fatty acids (FA) have gained notoriety for their role
A Goc et al.
Journal of applied microbiology, 123(3), 637-650 (2017-06-24)
Borrelia sp., a causative pathogenic factor of Lyme disease (LD), has become a major public health threat. Current treatments based on antibiotics often lead to relapse after their withdrawal. Naturally derived substances that could work synergistically to display higher efficacy
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