1162002

シトシンβ-D-アラビノフラノシド

United States Pharmacopeia (USP) Reference Standard

• 別名: (β-D-アラビノフラノシル)シトシン, Ara-C, アラビノシチジン, アラビノシルシトシン, シタラビン, シトシンアラビノシド
• 実験式（ヒル表記法）: C₉H₁₃N₃O₅
• CAS番号: 147-94-4
• 分子量: 243.22
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749501
• MDL number: MFCD00066487
• Beilstein/REAXYS Number: 89175

特性

• grade: pharmaceutical primary standard
• agency: USP
• API family: cytarabine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O
• InChI: 1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
• InChI key: UHDGCWIWMRVCDJ-CCXZUQQUSA-N
• Gene Information: human ... POLA1(5422), POLA2(23649), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558)

詳細

General description

Find answers to frequently asked questions on USP products in USP FAQs.

この製品は薬局方標準品です。発行元の薬局方により製造・供給されています。詳しい情報は、発行元の薬局方のウェブサイトよりご確認ください。

Application

Cytarabine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Cytarabine for Injection

Biochem/physiol Actions

Ara-CはDNAに取り込まれてI型トポイソメラ-ゼとの間に切断複合体を形成することでDNAを断片化し、DNAの複製を阻害します。RNA合成には影響を及ぼしません。抗白血病薬。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

安全性情報

• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pictograms: GHS08
• signalword: Danger
• hcodes: H340,H361fd
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Muta. 1B - Repr. 2
• 保管分類: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects