- AS2077715: a novel antifungal antibiotic produced by Capnodium sp. 339855.
AS2077715: a novel antifungal antibiotic produced by Capnodium sp. 339855.
The Journal of antibiotics (2014-05-29)
Keisuke Ohsumi, Teruhisa Masaki, Shigehiro Takase, Masato Watanabe, Akihiko Fujie
PMID24865863
ABSTRAKT
A novel antifungal agent, AS2077715, was isolated from the fermentation broth of a fungal strain (339855) identified as a new Capnodium species based on morphological characteristics and large-subunit ribosomal DNA sequencing. AS2077715 was isolated as a white powder via solvent extraction, HP-20 and ODS-B column chromatography and crystallization, and was determined to have the molecular formula C25H41NO7. AS2077715 has a structure related to that of funiculosin, an inhibitor of mitochondrial cytochrome bc1 complex (complex III), and showed antifungal activity against Trichophyton species.
MATERIAŁY
Numer produktu
Marka
Opis produktu
Sigma-Aldrich
8-Octanoyloxypyrene-1,3,6-trisulfonic acid trisodium salt, suitable for fluorescence, ≥90% (HPCE)
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Dimethyl sulfoxide, meets EP testing specifications, meets USP testing specifications
Sigma-Aldrich
Dimethyl sulfoxide, Hybri-Max™, sterile-filtered, BioReagent, suitable for hybridoma, ≥99.7%
Sigma-Aldrich
Dimethyl sulfoxide, sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma
Dimethyl sulfoxide, European Pharmacopoeia (EP) Reference Standard
Supelco
Residual Solvent - Chloroform, Pharmaceutical Secondary Standard; Certified Reference Material