890890P

18:1 TAP (DOTAP)

Avanti Research^™ - A Croda Brand

• 别名: 1,2-二油酰基-3-三甲基铵-丙烷 (氯盐), DOTAP
• 经验公式（希尔记法）: C₄₂H₈₀NO₄Cl
• 化学文摘社编号: 132172-61-3
• 分子量: 698.54
• MDL number: MFCD01310872
• UNSPSC Code: 12352211
• NACRES: NA.25

属性

• 产品名称: 18:1 TAP (DOTAP), Avanti Research^™ - A Croda Brand
• SMILES string: [H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]
• InChI: 1S/C42H80NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h20-23,40H,6-19,24-39H2,1-5H3;1H/q+1;/p-1/b22-20-,23-21-;
• InChI key: KSXTUUUQYQYKCR-LQDDAWAPSA-M
• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 g ((890890P-1G)); pkg of 2 × 100 mg ((890890P-200MG)); pkg of 5 × 100 mg ((890890P-100MG)); pkg of 1 × 25 mg ((890890P-25MG))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• application(s): advanced drug delivery
• lipid type: transfection; cationic lipids
• shipped in: dry ice
• storage temp.: −20°C

说明

Application

18:1 TAP (DOTAP)可用于在氯仿溶液中形成干膜，制备阳离子脂质体。[1]也用于标准储备溶液中，制备阳离子脂质体。[2]

Biochem/physiol Actions

DOTAP（1,2-二油酰基-3-三甲基铵-丙烷）为阳离子脂质结构，用于体内和体外核酸和蛋白递送。[3]脂质组成和细胞类型会影响 DOTAP 的转染潜能。[4]DOTAP介导造血干细胞(HSCs)的基因敲低技术。[5]

Packaging

5 mL透明玻璃密封安瓿瓶(890890P-200mg)

5 mL透明玻璃密封安瓿瓶(890890P-25mg)

5 mL透明玻璃密封安瓿瓶(890890P-500mg)

60 mL琥珀色宽口螺帽玻璃瓶(890890P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全信息

• 存储类别: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable