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MilliporeSigma

82435

Puerarin

≥98.0% (HPLC)

Synonym(s):

8-(β-D-Glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kakonein

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5 MG

$456.00

$456.00

List Price$608.00Save 25%

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About This Item

Empirical Formula (Hill Notation):
C21H20O9
CAS Number:
Molecular Weight:
416.38
Beilstein/REAXYS Number:
64198
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

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Quality Level

assay

≥98.0% (HPLC)

form

powder

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)ccc3C(=O)C(=COc23)c4ccc(O)cc4

InChI

1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1

InChI key

HKEAFJYKMMKDOR-VPRICQMDSA-N

Gene Information

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This Item
P5555PHL8931818854
form

powder

form

-

form

powder

form

powder

assay

≥98.0% (HPLC)

assay

~80% (HPLC)

assay

≥95.0% (HPLC)

assay

≥90.0% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

Gene Information

mouse ... Aldh1a2(19378), Maoa(17161)

Gene Information

mouse ... Aldh1a2(19378), Maoa(17161)

Gene Information

-

Gene Information

-

Biochem/physiol Actions

Isoflavone component of kudzu. Reduces anxiety symptoms associated with alcohol withdrawal.[1]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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David H Overstreet et al.
Pharmacology, biochemistry, and behavior, 75(3), 619-625 (2003-08-05)
Because extracts of kudzu have been used as a hangover remedy in China for many centuries, we tested the ability of NPI-031G (puerarin), an isoflavone isolated from kudzu, to counteract anxiogenic effects associated with withdrawal from chronic alcohol exposure. NPI-O31G
Feng Tian et al.
Neuroscience letters, 543, 64-68 (2013-04-11)
Puerarin extracted from radix puraeriae is shown to exert a variety of pharmacological effects including neuroprotective properties. However, its mechanisms of action are needed to further explore. The study was designed to investigate the mechanism of puerarin treatment of acute
Rong Li et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 52, 69-75 (2012-11-14)
This study was designed to evaluate the potential effects of puerarin (PR), an effective isoflavonoid compound purified from Pueraria lobata, in treating hepatic fibrosis (HF) rats induced by carbon tetrachloride (CCl(4), 2 mL kg(-1) d(-1)). Compared to model control, PR
Li Jiang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 915-916, 8-12 (2013-01-15)
Gastrodin (Gas) and puerarin (Pur) are bioactive substances derived from traditional Chinese medicine Gastrodia elata and Radix Puerariae, respectively, which were often used together in Chinese clinical prescriptions. Their injections were used in combined way for treatment of some cardiocerebrovascular
Y Zou et al.
Free radical research, 47(1), 55-63 (2012-10-24)
Current evidence suggests that amyloid beta (Aβ) peptides may play a major role in the pathogenesis of Alzheimer's disease in part by eliciting oxidative stress. Puerarin, a major isoflavone glycoside from Kudzu root (Pueraria lobata), has been reported to exert

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