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184314

Tetrahydrofuran-d8

≥99.5 atom % D

Synonym(s):

THF-d8, Deuterated tetrahydrofuran, Octadeuterotetrahydrofuran

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$94.40

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$350.00

10 G

$567.00

$94.40

Estimated to ship onDecember 15, 2025fromMILWAUKEE

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About This Item

Empirical Formula (Hill Notation):
C4D8O
CAS Number:
1693-74-9
Molecular Weight:
80.16
Beilstein/REAXYS Number:
111854
MDL number:
MFCD00044238
UNSPSC Code:
12142201
PubChem Substance ID:
24851108
NACRES:
NA.21

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isotopic purity

≥99.5 atom % D

assay

≥99% (CP)

form

liquid

technique(s)

NMR: suitable

impurities

≤0.03% water
water

refractive index

n20/D 1.403 (lit.)

bp

65-66 °C (lit.)

mp

−106 °C (lit.)

density

0.985 g/mL at 25 °C (lit.)

mass shift

M+8

storage temp.

2-8°C

SMILES string

[2H]C1([2H])OC([2H])([2H])C([2H])([2H])C1([2H])[2H]

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2/i1D2,2D2,3D2,4D2

InChI key

WYURNTSHIVDZCO-SVYQBANQSA-N

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This Item
441406437727269891
Tetrahydrofuran-d8 ≥99.5 atom % D

Sigma-Aldrich

184314

Tetrahydrofuran-d8

Tetrahydrofuran-d8 ≥99.5 atom % D

Sigma-Aldrich

441406

Tetrahydrofuran-d8

Tetrahydrofuran-d8 ≥99.5 atom % D, contains 0.03 % (v/v) TMS

Sigma-Aldrich

437727

Tetrahydrofuran-d8

Tetrahydrofuran-d8 ≥99.5 atom % D, contains 1 % (v/v) TMS

Sigma-Aldrich

269891

Tetrahydrofuran-d8

isotopic purity

≥99.5 atom % D

isotopic purity

≥99.5 atom % D

isotopic purity

≥99.5 atom % D

isotopic purity

≥99.5 atom % D

technique(s)

NMR: suitable

technique(s)

NMR: suitable

technique(s)

NMR: suitable

technique(s)

NMR: suitable

assay

≥99% (CP)

assay

≥99% (CP)

assay

≥99% (CP)

assay

≥99% (CP)

mass shift

M+8

mass shift

M+8

mass shift

M+8

mass shift

M+8

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

liquid

form

liquid

form

liquid

form

liquid

General description

Tetrahydrofuran-d8 (THF-d8), a deuterated derivative of tetrahydrofuran, is a standard purity solvent suitable for routine NMR analyses (conducted at ambient temperatures where quality is less critical). It participates as a solvent in an intermolecular proton exchange reaction between methanol and acetic acid. Kinetics of this reaction has been studied by ′H NMR line shape analysis.[1] Infrared spectral studies of THF and THF-d8 have been investigated in the range of 10 and 300cm-1.[2]
Tetrahydrofuran-d8 may be used as a solvent in the synthesis of deuteriotris[bis(trimethylsilyl)amido]thorium and deuteriotris[bis(trimethylsiiyl)amido]uranium.[3]

Other Notes

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Respiratory system

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

1.4 °F - closed cup

flash_point_c

-17 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MBBF1151
MBBF0495
MBBF0358
MBBF0222
MBBD9025

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Far-Infrared Spectrum of Tetrahydrofuran: Spectroscopic Evidence for Pseudorotation.
Lafferty WJ, et al.
J. Chem. Phys. , 42(8), 2915-2919 (1965)
NMR lineshape theory of superimposed intermolecular spin exchange reactions and its action to the system acetic acid/methanol/tetrahydrofuran-d8.
Limbach HH.
Journal of Magnetic Resonance, 36(3), 287-300 (1979)
Dynamic NMR study of the interference between cyclic proton exchange, selfassociation and hindered rotation of diphenylformamidine in tetrahydrofuran.
Meschede L, et al.
Berichte der Bunsengesellschaft fur physikalische Chemie, 92(4), 469-485 (1988)
Alejandro G Lichtscheidl et al.
Dalton transactions (Cambridge, England : 2003), 44(36), 16156-16163 (2015-08-22)
The synthesis and full characterization, including Nuclear Magnetic Resonance (NMR) data ((1)H, (13)C{(1)H} and (119)Sn{(1)H}), for a series of Me3SnX (X = O-2,6-(t)Bu2C6H3 (), (Me3Sn)N(2,6-(i)Pr2C6H3) (), NH-2,4,6-(t)Bu3C6H2 (), N(SiMe3)2 (), NEt2, C5Me5 (), Cl, Br, I, and SnMe3) compounds in

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NMR Deuterated Solvent Properties Reference Chart

Use this reference table to find the coupling values and chemical shifts of our NMR (deuterated) solvents. Melting and boiling points, molecular weight, density, and CAS number are also listed.

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