391425

Sigma-Aldrich

1-Acetylpyrene

97%

Empirical Formula (Hill Notation):
C18H12O
CAS Number:
Molecular Weight:
244.29
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

97%

mp

86-89 °C (lit.)

SMILES string

CC(=O)c1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C18H12O/c1-11(19)15-9-7-14-6-5-12-3-2-4-13-8-10-16(15)18(14)17(12)13/h2-10H,1H3

Inchi Key

KCIJNJVCFPSUBQ-UHFFFAOYSA-N

Related Categories

General description

1-Acetylpyrene is a pyrene derivative. Its synthesis has been reported. Its phytophysical properties have been studied using absolute fluorescence quantum yield measurement and time-dependent density functional theory (TD-DFT) calculations. Its ability to interact with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition has been reported. Its function as an environment-sensitive fluorophore has been investigated.

Application

1-Acetylpyrene is suitable for use in a comparative study on the photoinitiating efficiency of pyrene, 1-acetylpyrene and 1-(bromoacetyl)pyrene for copolymerization of styrene with acrylonitrile. It may be used in the following studies:
  • As a starting material in the synthesis of ethynlypyrene. 1-(1-chlorovinyl)pyrene was also isolated during this reaction.
  • As a starting material in the synthesis of substituted pyrene derivatives incorporated heterocyclic and sugar moieties.
  • Synthesis of (E)-pyrene oxime ester conjugates of carboxylic acids.
  • Synthesis of tertiary alcohols based on 1-acetylpyrene.
  • Synthesis of (E)-N-[1-(pyren-1-yl)ethylidene]chrysene-2-amine.
  • Synthesis of 3,3-di(methylsulfanyl)-1-(1-pyrenyl)-2-propen-1-one.

Packaging

10 g in glass bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Synthesis and study of film-forming properties and light sensitivity of 4-acyloxy-3-methoxy (ethoxy) phenylmethylidene-(chrysen-2-yl) amines.
Dikusar EA, et al.
Russ. J. Gen. Chem., 77(2), 278-281 (2007)
Synthesis and fluorescent properties of 5-(1-pyrenylethynyl)-2'-deoxyuridine-containing oligodeoxynucleotides.
Malakhov AD, et al.
Russian J. Bioorg. Chem., 26(1), 34-44 (2000)
Fundamental photoluminescence properties of pyrene carbonyl compounds through absolute fluorescence quantum yield measurement and density functional theory.
Niko Y, et al.
Tetrahedron, 68(31), 6177-6185 (2012)
Tertiary alcohols based on 1-acetylpyrene.
Dikusar EA.
Russ. J. Org. Chem., 43(10), 1492-1494 (2007)
Synthesis, characterization and pharmacological investigations of some novel heterocyclic derivatives incorporating pyrene and sugar moieties.
Khalifa NM, et al.
Research on Chemical Intermediates, 40(4), 1565-1574 (2014)

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