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1.06447

tri-Sodium citrate dihydrate

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS, E 331

Synonym(s):

Sodium citrate tribasic dihydrate, Trisodium Citrate, Sodium Citrate, Dihydrate, Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate

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Pack SizeSKUAvailabilityPrice
1 kg

Estimated to ship TODAY

$112.00
5 kg

Estimated to ship onJune 05, 2026

$308.00
12 kg

Estimated to ship onMay 26, 2026

$523.00
3 x 1 kg

Estimated to ship onMay 11, 2026

$755.00
25 kg

About This Item

Linear Formula:
HOC(COONa)(CH2COONa)2 · 2H2O
CAS Number:
Molecular Weight:
294.10
UNSPSC Code:
12352107
EC Index Number:
200-675-3
E Number:
E331
MDL number:
Beilstein/REAXYS Number:
6104939

$112.00


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Quality Level

agency

USP, BP, ChP, JP, Ph. Eur., suitable for SM 4500 - NH3

product line

EMPROVE® EXPERT

form

solid

feature

RNase and DNase free

impurities

endotoxins, low

pH

7.5-9.0 (25 °C, 50 g/L in H2O)

pKa 

(1) 3.1, (2) 4.8, (3) 6.4

mp

150 °C (anhydrous substance), >300 °C (lit.)

application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

2-30°C

SMILES string

O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3

InChI key

NLJMYIDDQXHKNR-UHFFFAOYSA-K

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium citrate dihydrate is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
1.064461.06432PHR1416
application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation
solid formulation

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

application(s)

pharmaceutical (small molecule)

agency

BP, JP, USP, ChP, suitable for SM 4500 - NH3, Ph. Eur.

agency

BP, JP, Ph. Eur., USP

agency

BP, JP, Ph. Eur., USP

agency

traceable to USP 1613859

form

solid

form

powder, solid

form

crystalline, solid

form

-

product line

EMPROVE® EXPERT

product line

EMPROVE® ESSENTIAL

product line

EMPROVE® ESSENTIAL

product line

-

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

impurities

endotoxins, low

impurities

-

impurities

-

impurities

-


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Related Content

Learn more on mAb subcutaneous or intravenous formulation, and the relevant associated products, including excipients.

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.





Global Trade Item Number

SKUGTIN
106447100004022536076928
106447500004022536076942
106447000104027269279790
106447901204065270749765
106447902904022536940328
106447905104065272192576
106447910004065269082651
106447950004065271155183

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