The reactivity and instability of the compound is likely due to the high number of unsaturated double bonds in its chemical structure.
201102
Bilirubin Conjugate, Ditaurate, Disodium Salt
solid, bilirubin standard, Calbiochem®
Synonym(s):
Bilirubin ditaurate (BDT)
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Product Name
Bilirubin Conjugate, Ditaurate, Disodium Salt, Bilirubin Conjugate, Ditaurate, Disodium Salt is suitable as a direct bilirubin standard. Behaves similar to purified bilirubin glucuronides from human bile in diazo tests. Unstable in solution.
description
RTECS - DU3038000
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
protect from light
solubility
water: 10 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
Related Categories
1 of 4
This Item | 2011 | 203800 | 309795 |
|---|---|---|---|
| form solid | form solid | form solid | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® | manufacturer/tradename Calbiochem® |
| storage temp. −20°C | storage temp. 10-30°C | storage temp. −20°C | storage temp. −20°C |
| solubility water: 10 mg/mL | solubility chloroform: 1 mg/mL, alkaline solution: soluble | solubility water: soluble | solubility water: 0.5% |
| storage condition OK to freeze, protect from light, desiccated (hygroscopic) | storage condition OK to freeze, protect from light | storage condition OK to freeze, desiccated (hygroscopic) | storage condition OK to freeze, desiccated, protect from light |
Application
Bilirubin Conjugate, Ditaurate, Disodium Salt has been used to spike patient samples to access icterus interference.[1] It has also been used to prepare test pools for conjugated bilirubin to screen bilirubin interference.[2]
Bilirubin Conjugate, Ditaurate, Disodium Salt – Calbiochem has been used as a standard for testing the interference of conjugated bilirubin in assays aimed at quantifying analytes in serum or plasma samples.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Suitable as a direct bilirubin standard
Suitable as a direct bilirubin standard
Product does not compete with ATP.
Reversible: no
Disclaimer
Toxicity: Standard Handling (A)
General description
Bilirubin ditaurate (BDT) is the first bile pigment found naturally in the biles of specific fish species. It consists of unconjugated bilirubin (UCB) with taurine side chains attached to the C8 and C12 propionic acids, similar in length to glucuronic acids.[3]
Packaging
Packaged under inert gas
Preparation Note
Unstable in solution; reconstitute just prior to use.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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A novel canine nuclear magnetic resonance spectroscopy-based metabolomics platform: Validation and sample handling
Ottka C, et al.
Veterinary Clinical Pathology / American Society For Veterinary Clinical Pathology (2021)
Self-assembly of aqueous bilirubin ditaurate, a natural conjugated bile pigment, to contraposing enantiomeric dimers and M(-) and P(+) tetramers and their selective hydrophilic disaggregation by monomers and micelles of bile salts
Neubrand MW, et al.
Biochemistry (2015)
Toan Huynh et al.
Cureus, 9(12), e1965-e1965 (2018-03-02)
Objective We aimed to find new methods to detect and quantify hemolysis and icterus which may cause assay biases. These methods need to determine each of these interferents in the presence of various other interferents. They also need to have
Rising above helium: A hydrogen carrier gas chromatography flame ionization detection (GC-FID) method for the simultaneous quantification of toxic alcohols and ethylene glycol in human plasma specimens
Buse J, et al.
Clinical Biochemistry (2019)
Diane M Hamlin et al.
Kidney360, 3(2), 341-356 (2022-04-05)
Symmetric dimethylarginine (SDMA) is an excretory renal function biomarker shown to correlate well with glomerular filtration rate in dogs, cats, humans, and rats. The objectives of this study were to determine utility of serum SDMA as a renal biomarker in
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