Skip to Content
MilliporeSigma

375095

Heparin, Sodium Salt, Porcine Intestinal Mucosa

Synonym(s):

Heparin, Sodium Salt, Porcine Intestinal Mucosa, HEP, Na

Slide 1 of 1
Sign In to View Organizational & Contract Pricing

Select a Size

100 KU

$109.00

500 KU

$395.00

$109.00

Check Cart for Availability
Request a Bulk Order

About This Item

CAS Number:
9041-08-1
MDL number:
MFCD00081689
UNSPSC Code:
12352201
NACRES:
NA.79

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

description

Merck USA index - 14, 4653

Quality Level

100

form

lyophilized

specific activity

≥160 USP units/mg dry wt

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

≤0.5 EU/mg Endotoxin

solubility

water: 50 mg/mL

shipped in

ambient

storage temp.

15-25°C

SMILES string

[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O

InChI

1S/C26H42N2O37S5.Na/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36;/h5-20,23-26,28-29,31-

InChI key

JRTRSJGZMRQDHI-UHFFFAOYSA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
H4784H5515SRE0027
Heparin, Sodium Salt, Porcine Intestinal Mucosa

Millipore

375095

Heparin, Sodium Salt, Porcine Intestinal Mucosa

Heparin sodium salt from porcine intestinal mucosa ≥180 USP units/mg

Sigma-Aldrich

H4784

Heparin sodium salt from porcine intestinal mucosa

Heparin sodium salt from porcine intestinal mucosa ≥150 IU/mg (dry basis)

Sigma-Aldrich

H5515

Heparin sodium salt from porcine intestinal mucosa

Sigma-Aldrich

Sigma-Aldrich

SRE0027

Heparin sodium porcine mucosa

solubility

water: 50 mg/mL

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

solubility

H2O: 50 mg/mL, clear, colorless to faintly yellow

solubility

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

400

form

lyophilized

form

powder

form

powder

form

powder

storage temp.

15-25°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

-

impurities

≤0.5 EU/mg Endotoxin

impurities

-

impurities

-

impurities

-

description

Merck USA index - 14, 4653

description

-

description

-

description

-

General description

M.W. 13,500-15,000. Note: 1 KU = 1000 units.
MW: 15,000 ± 2,000
Preservative-free, non-sterile. Highly sulfated dextrorotatory mucopolysaccharide with specific anticoagulant properties. Inhibits IP3-activated Ca2+ channel release of the endoplasmic reticulum. Reported to activate the ryanodine receptor. Note: 1 KU = 1000 units. MW: 15,000 ± 2,000.

Other Notes

Seuwen, K., and Boddeke, H.G. 1995. Br. J. Pharmacol.114, 1613.
Ehrlich, B.E., et al. 1994. Trends Pharmacol. Sci.15,145.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Enrique Gómez et al.
Journal of proteome research, 19(3), 1169-1182 (2020-01-25)
Metabolomics may identify biomarkers in blood that differentiate pregnant from open embryo recipients. Fresh and vitrified/warmed, in vitro-produced embryos were transferred to Holstein recipients (discovery group). Recipient blood plasma collected on Day-0 (estrus) and Day-7 (before embryo transfer) were analyzed
Junxin Wang et al.
Bioconjugate chemistry, 29(11), 3768-3775 (2018-10-04)
We recently reported a real-time method to measure heparin in human whole blood based on the photoacoustic change of methylene blue (MB). Intriguingly, the MB behaved unlike other "turn on" photoacoustic probes-the absorbance decreased as the photoacoustic signal increased. The

Questions

1–2 of 2 Questions  

  1. I plan to use heparin in Neurobasal medium for culturing GBM cells. Literature suggests 2 µg/mL, but I need the units/mL for the final concentration. Could you provide guidance on the correct units/mL for heparin?

    1 answer

    1. Product 375095 is assayed for activity on a batch to batch basis with a specification for this product ≥160 USP units/mg dry weight. The reported activity value for this product will be found on the certificate of analysis for a given lot. It is unclear as to what activity corresponds to the provided concentration that was indicated and only the authors of the literature citation would know. Certain research articles do provide information on the activity of heparin to supplement neurobasal medium (NBM). Please see the article below which states NBM can be supplemented with 100 U/uL heparin. This decision will be at the discretion of the end user.

      https://www.sciencedirect.com/science/article/pii/S2666166723004884

      Helpful?

  2. What should be the storage temperature after 100 000 units of heparin salt is dissolved in 100 mL of PBS 1x

    1 answer

    1. Sterile filtered heparin solutions remain stable for up to 2 years when stored at 2-8 °C, provided th. Autoclaving and freezing heparin solutions are not recommended. Please see the link below to review additional information available in the datasheet for similar product H3393:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/112/608/h3393pis.pdf

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service